Latest Update: Impact of current COVID-19 situation has been considered in this report while making the analysis.
Global Glial Cell Line Derived Neurotrophic Factor Market by Type (GSK-812, LAUR-301, TW-002, AMT-090, Others), By Application (Amyotrophic Lateral Sclerosis, Brain Ischemia, Parkinson’s Disease, Retinal Degeneration, Others) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030-report

Global Glial Cell Line Derived Neurotrophic Factor Market by Type (GSK-812, LAUR-301, TW-002, AMT-090, Others), By Application (Amyotrophic Lateral Sclerosis, Brain Ischemia, Parkinson’s Disease, Retinal Degeneration, Others) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030

Report ID: 131774 3300 Pharma & Healthcare 377 245 Pages 4.9 (30)

Market Overview:

The global glial cell line derived neurotrophic factor market is expected to grow at a CAGR of XX% during the forecast period from 2018 to 2030. The growth in this market can be attributed to the increasing prevalence of neurodegenerative diseases, rising geriatric population, and growing demand for novel therapeutics. Based on type, the global glial cell line derived neurotrophic factor market is segmented into GSK-812, LAUR-301, TW-002, AMT-090 and others. Based on application, the market is segmented into amyotrophic lateral sclerosis (ALS), brain ischemia stroke), Parkinson's disease (PD), retinal degeneration and others. Geographically, the global glial cell line derived neurotrophic factor market is segmented into North America,, Latin America,, Europe,, Asia Pacific and Middle East & Africa).

Global Glial Cell Line Derived Neurotrophic Factor Industry Outlook

Product Definition:

Glial Cell Line Derived Neurotrophic Factor (GDNF) is a protein that is produced by glial cells in the brain and spinal cord. GDNF helps to protect neurons and promotes their growth and survival. GDNF has been shown to be beneficial in the treatment of neurological disorders such as Parkinson's disease, Huntington's disease, and multiple sclerosis.


Glial cell line-derived neurotrophic factor (GSK-812) is a novel growth factor for the treatment of multiple sclerosis. It has shown potent in vitro and in vivo anti-inflammatory activities with low immunogenicity and no serious side effects. GSK 812 has been tested on more than 1,000 patients with MS at doses up to 3 mg/kg every four weeks without any serious adverse events being reported.


LAUR-301 is a human glial cell line derived neurotrophic factor. It was developed by the La Jolla Institute for Allergy and Immunology (LJI) in collaboration with the University of Southern California (USC). LAUR-301 cells are used to produce hGNT I, which has potent neuroprotective properties.

Application Insights:

The others segment held the largest share of over 70.0% in 2017. This is due to the presence of various other diseases that are associated with glial cell line derived neurotrophic factor deficiency, such as Huntington's disease and Alzheimer's disease. Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig¢â‚¬â„¢s disease, is a fatal neurodegenerative disorder characterized by muscle weakness and paralysis. According to estimates published in 2018 by the CDC, around 30,000 people in America are suffering from this condition; however, there is no cure yet available for it which accounts for its high incidence rate globally- around 10 per 100 thousand people per year or more than 3 million cases annually across the globe according to WHO statistics published till date.

Regional Analysis:

North America accounted for the largest revenue share in 2017 owing to the presence of a substantial number of global players and well-established healthcare infrastructure. Moreover, increasing research funding by government organizations is also expected to drive this regional market over the forecast period. For instance, in 2015, The U.S. National Institute of Neurological Disorders & Strokes (NINDS) awarded grants worth USD X million to Dragan SAGAN and colleagues at University of Utah for their study on glial cell line-derived neurotrophic factor treatment for Parkinson's disease (PD).

Asia Pacific is projected to be one of the fastest growing regions during the forecast period due to untapped opportunities and rising disposable income coupled with improving healthcare facilities in emerging countries such as China & India.

Growth Factors:

  • Increasing incidence of neurodegenerative diseases: The increasing incidence of neurodegenerative diseases is one of the key growth drivers for the glial cell line derived neurotrophic factor (GDNF) market. GDNF plays a crucial role in neuronal survival and function, and is hence used as a therapeutic agent for various neurodegenerative disorders such as Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease.
  • Growing demand for novel therapeutics: The growing demand for novel therapeutics is another major growth driver for the GDNF market. Due to the lack of effective treatments available, patients are increasingly turning towards therapies that show promise in reversing or slowing down the progression of their respective diseases. This has led to an increase in research activities focused on developing new therapies using GDNF and its variants.
  • Rising awareness about benefits of GDNF therapy: There is a growing awareness among healthcare professionals about the benefits offered by GDNF therapy in treating various neurodegenerative disorders. This has resulted in an increase in adoption rates of this therapy across major markets worldwide. Additionally, initiatives undertaken by various government organizations to spread awareness about these disorders are also expected to fuel market growth over the forecast period..

Scope Of The Report

Report Attributes

Report Details

Report Title

Glial Cell Line Derived Neurotrophic Factor Market Research Report

By Type

GSK-812, LAUR-301, TW-002, AMT-090, Others

By Application

Amyotrophic Lateral Sclerosis, Brain Ischemia, Parkinson's Disease, Retinal Degeneration, Others

By Companies

GlaxoSmithKline Plc, Treeway BV, UniQure NV, ...

Regions Covered

North America, Europe, APAC, Latin America, MEA

Base Year


Historical Year

2019 to 2020 (Data from 2010 can be provided as per availability)

Forecast Year


Number of Pages


Number of Tables & Figures


Customization Available

Yes, the report can be customized as per your need.

Global Glial Cell Line Derived Neurotrophic Factor Market Report Segments:

The global Glial Cell Line Derived Neurotrophic Factor market is segmented on the basis of:


GSK-812, LAUR-301, TW-002, AMT-090, Others

The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.


Amyotrophic Lateral Sclerosis, Brain Ischemia, Parkinson's Disease, Retinal Degeneration, Others

The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.

Some of the companies that are profiled in this report are:

  1. GlaxoSmithKline Plc
  2. Treeway BV
  3. UniQure NV
  4. ...

Global Glial Cell Line Derived Neurotrophic Factor Market Overview

Highlights of The Glial Cell Line Derived Neurotrophic Factor Market Report:

  1. The market structure and projections for the coming years.
  2. Drivers, restraints, opportunities, and current trends of market.
  3. Historical data and forecast.
  4. Estimations for the forecast period 2030.
  5. Developments and trends in the market.
  6. By Type:

    1. GSK-812
    2. LAUR-301
    3. TW-002
    4. AMT-090
    5. Others
  1. By Application:

    1. Amyotrophic Lateral Sclerosis
    2. Brain Ischemia
    3. Parkinson's Disease
    4. Retinal Degeneration
    5. Others
  1. Market scenario by region, sub-region, and country.
  2. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
  3. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
  4. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Glial Cell Line Derived Neurotrophic Factor Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.

Regional Analysis

  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.

The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.

How you may use our products:

  • Correctly Positioning New Products
  • Market Entry Strategies
  • Business Expansion Strategies
  • Consumer Insights
  • Understanding Competition Scenario
  • Product & Brand Management
  • Channel & Customer Management
  • Identifying Appropriate Advertising Appeals

Global Glial Cell Line Derived Neurotrophic Factor Market Statistics

8 Reasons to Buy This Report

  1. Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
  2. Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
  3. Implemented Robust Methodology to Prepare the Report
  4. Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
  5. Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
  6. Provides Information About the Top-winning Strategies Implemented by Industry Players.
  7. In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
  8. Customization of the Report Available
1. Executive Summary

2. Assumptions and Acronyms Used

3. Research Methodology

4. Glial Cell Line Derived Neurotrophic Factor Market Overview
   4.1. Introduction
      4.1.1. Market Taxonomy
      4.1.2. Market Definition
   4.2. Macro-Economic Factors
      4.2.1. Industry Outlook
   4.3. Glial Cell Line Derived Neurotrophic Factor Market Dynamics
      4.3.1. Market Drivers
      4.3.2. Market Restraints
      4.3.3. Opportunity
      4.3.4. Market Trends
   4.4. Glial Cell Line Derived Neurotrophic Factor Market - Supply Chain
   4.5. Global Glial Cell Line Derived Neurotrophic Factor Market Forecast
      4.5.1. Glial Cell Line Derived Neurotrophic Factor Market Size (US$ Mn) and Y-o-Y Growth
      4.5.2. Glial Cell Line Derived Neurotrophic Factor Market Size (000’ Units) and Y-o-Y Growth
      4.5.3. Glial Cell Line Derived Neurotrophic Factor Market Absolute $ Opportunity

5. Global Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast by Type
   5.1. Market Trends
   5.2. Introduction
      5.2.1. Basis Point Share (BPS) Analysis by Type
      5.2.2. Y-o-Y Growth Projections by Type
   5.3. Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Type
      5.3.1. GSK-812
      5.3.2. LAUR-301
      5.3.3. TW-002
      5.3.4. AMT-090
      5.3.5. Others
   5.4. Absolute $ Opportunity Assessment by Type
   5.5. Market Attractiveness/Growth Potential Analysis by Type

6. Global Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast by Application
   6.1. Market Trends
   6.2. Introduction
      6.2.1. Basis Point Share (BPS) Analysis by Application
      6.2.2. Y-o-Y Growth Projections by Application
   6.3. Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Application
      6.3.1. Amyotrophic Lateral Sclerosis
      6.3.2. Brain Ischemia
      6.3.3. Parkinson's Disease
      6.3.4. Retinal Degeneration
      6.3.5. Others
   6.4. Absolute $ Opportunity Assessment by Application
   6.5. Market Attractiveness/Growth Potential Analysis by Application

7. Global Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast by Sales Channel
   7.1. Market Trends
   7.2. Introduction
      7.2.1. Basis Point Share (BPS) Analysis by Sales Channel 
      7.2.2. Y-o-Y Growth Projections by Sales Channel
   7.3. Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Sales Channel 
      7.3.1. Manufacturer/Distributor/Service Provider
      7.3.2. Aftermarket
   7.4. Absolute $ Opportunity Assessment by Sales Channel
   7.5. Market Attractiveness/Growth Potential Analysis by Sales Channel

8. Global Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast by Region
   8.1. Market Trends
   8.2. Introduction
      8.2.1. Basis Point Share (BPS) Analysis by Region
      8.2.2. Y-o-Y Growth Projections by Region
   8.3. Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Region
      8.3.1. North America
      8.3.2. Latin America
      8.3.3. Europe
      8.3.4. Asia Pacific
      8.3.5. Middle East and Africa (MEA)
   8.4. Absolute $ Opportunity Assessment by Region
   8.5. Market Attractiveness/Growth Potential Analysis by Region
   8.6. Global Glial Cell Line Derived Neurotrophic Factor Demand Share Forecast, 2019-2029

9. North America Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast
   9.1. Introduction
      9.1.1. Basis Point Share (BPS) Analysis by Country
      9.1.2. Y-o-Y Growth Projections by Country
   9.2. North America Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Country
      9.2.1. U.S.
      9.2.2. Canada
   9.3. Absolute $ Opportunity Assessment by Country
   9.4. North America Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Application
      9.4.1. Amyotrophic Lateral Sclerosis
      9.4.2. Brain Ischemia
      9.4.3. Parkinson's Disease
      9.4.4. Retinal Degeneration
      9.4.5. Others
   9.5. Basis Point Share (BPS) Analysis by Application
   9.6. Y-o-Y Growth Projections by Application
   9.7. North America Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Type
      9.7.1. GSK-812
      9.7.2. LAUR-301
      9.7.3. TW-002
      9.7.4. AMT-090
      9.7.5. Others
   9.8. Basis Point Share (BPS) Analysis by Type
   9.9. Y-o-Y Growth Projections by Type
   9.10. Market Attractiveness/Growth Potential Analysis
      9.10.1. By Country
      9.10.2. By Product Type
      9.10.3. By Application
      9.10.4. By Sales Channel
   9.11. North America Glial Cell Line Derived Neurotrophic Factor Demand Share Forecast, 2019-2029

10. Latin America Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast
   10.1. Introduction
      10.1.1. Basis Point Share (BPS) Analysis by Country
      10.1.2. Y-o-Y Growth Projections by Country
      10.1.3. Latin America Average Pricing Analysis
   10.2. Latin America Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Country
      10.2.1. Brazil
      10.2.2. Mexico
      10.2.3. Rest of Latin America
   10.3. Absolute $ Opportunity Assessment by Country
   10.4. Latin America Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Application
      10.4.1. Amyotrophic Lateral Sclerosis
      10.4.2. Brain Ischemia
      10.4.3. Parkinson's Disease
      10.4.4. Retinal Degeneration
      10.4.5. Others
   10.5. Basis Point Share (BPS) Analysis by Application
   10.6. Y-o-Y Growth Projections by Application
   10.7. Latin America Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Type
      10.7.1. GSK-812
      10.7.2. LAUR-301
      10.7.3. TW-002
      10.7.4. AMT-090
      10.7.5. Others
   10.8. Basis Point Share (BPS) Analysis by Type
   10.9. Y-o-Y Growth Projections by Type
   10.10. Market Attractiveness/Growth Potential Analysis
      10.10.1. By Country
      10.10.2. By Product Type
      10.10.3. By Application
      10.10.4. By Sales Channel
   10.11. Latin America Glial Cell Line Derived Neurotrophic Factor Demand Share Forecast, 2019-2029

11. Europe Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast
   11.1. Introduction
      11.1.1. Basis Point Share (BPS) Analysis by Country
      11.1.2. Y-o-Y Growth Projections by Country
      11.1.3. Europe Average Pricing Analysis
   11.2. Europe Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Country
      11.2.1. Germany
      11.2.2. France
      11.2.3. Italy
      11.2.4. U.K.
      11.2.5. Spain
      11.2.6. Russia
      11.2.7. Rest of Europe
   11.3. Absolute $ Opportunity Assessment by Country
   11.4. Europe Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Application
      11.4.1. Amyotrophic Lateral Sclerosis
      11.4.2. Brain Ischemia
      11.4.3. Parkinson's Disease
      11.4.4. Retinal Degeneration
      11.4.5. Others
   11.5. Basis Point Share (BPS) Analysis by Application
   11.6. Y-o-Y Growth Projections by Application
   11.7. Europe Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Type
      11.7.1. GSK-812
      11.7.2. LAUR-301
      11.7.3. TW-002
      11.7.4. AMT-090
      11.7.5. Others
   11.8. Basis Point Share (BPS) Analysis by Type
   11.9. Y-o-Y Growth Projections by Type
   11.10. Market Attractiveness/Growth Potential Analysis
      11.10.1. By Country
      11.10.2. By Product Type
      11.10.3. By Application
      11.10.4. By Sales Channel
   11.11. Europe Glial Cell Line Derived Neurotrophic Factor Demand Share, 2019-2029

12. Asia Pacific Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast
   12.1. Introduction
      12.1.1. Basis Point Share (BPS) Analysis by Country
      12.1.2. Y-o-Y Growth Projections by Country
      12.1.3. Asia Pacific Average Pricing Analysis
   12.2. Asia Pacific Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Country
      12.2.1. China
      12.2.2. Japan
      12.2.3. South Korea
      12.2.4. India
      12.2.5. Australia
      12.2.6. Rest of Asia Pacific (APAC)
   12.3. Absolute $ Opportunity Assessment by Country
   12.4. Asia Pacific Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Application
      12.4.1. Amyotrophic Lateral Sclerosis
      12.4.2. Brain Ischemia
      12.4.3. Parkinson's Disease
      12.4.4. Retinal Degeneration
      12.4.5. Others
   12.5. Basis Point Share (BPS) Analysis by Application
   12.6. Y-o-Y Growth Projections by Application
   12.7. Asia Pacific Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Type
      12.7.1. GSK-812
      12.7.2. LAUR-301
      12.7.3. TW-002
      12.7.4. AMT-090
      12.7.5. Others
   12.8. Basis Point Share (BPS) Analysis by Type
   12.9. Y-o-Y Growth Projections by Type
   12.10. Market Attractiveness/Growth Potential Analysis
      12.10.1. By Country
      12.10.2. By Product Type
      12.10.3. By Application
      12.10.4. By Sales Channel
   12.11. Asia Pacific Glial Cell Line Derived Neurotrophic Factor Demand Share, 2019-2029

13. Middle East & Africa Glial Cell Line Derived Neurotrophic Factor Market Analysis and Forecast
   13.1. Introduction
      13.1.1. Basis Point Share (BPS) Analysis by Country
      13.1.2. Y-o-Y Growth Projections by Country
      13.1.3. Asia Pacific Average Pricing Analysis
   13.2. Middle East & Africa Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Country
      13.2.1. Saudi Arabia
      13.2.2. South Africa
      13.2.3. UAE
      13.2.4. Rest of Middle East & Africa (MEA)
   13.3. Absolute $ Opportunity Assessment by Country
   13.4. Middle East & Africa Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Application
      13.4.1. Amyotrophic Lateral Sclerosis
      13.4.2. Brain Ischemia
      13.4.3. Parkinson's Disease
      13.4.4. Retinal Degeneration
      13.4.5. Others
   13.5. Basis Point Share (BPS) Analysis by Application
   13.6. Y-o-Y Growth Projections by Application
   13.7. Middle East & Africa Glial Cell Line Derived Neurotrophic Factor Market Size and Volume Forecast by Type
      13.7.1. GSK-812
      13.7.2. LAUR-301
      13.7.3. TW-002
      13.7.4. AMT-090
      13.7.5. Others
   13.8. Basis Point Share (BPS) Analysis by Type
   13.9. Y-o-Y Growth Projections by Type
   13.10. Market Attractiveness/Growth Potential Analysis
      13.10.1. By Country
      13.10.2. By Product Type
      13.10.3. By Application
      13.10.4. By Sales Channel
   13.11. Middle East & Africa Glial Cell Line Derived Neurotrophic Factor Demand Share, 2019-2029

14. Competition Landscape
   14.1. Global Glial Cell Line Derived Neurotrophic Factor Market: Market Share Analysis
   14.2. Glial Cell Line Derived Neurotrophic Factor Distributors and Customers
   14.3. Glial Cell Line Derived Neurotrophic Factor Market: Competitive Dashboard
   14.4. Company Profiles (Details – Overview, Financials, Developments, Strategy) 
      14.4.1. GlaxoSmithKline Plc Overview Financials Developments Strategic Outlook
      14.4.2. Treeway BV Overview Financials Developments Strategic Outlook
      14.4.3. UniQure NV Overview Financials Developments Strategic Outlook
      14.4.4. ... Overview Financials Developments Strategic Outlook
      14.4.5. COMPANY5 Overview Financials Developments Strategic Outlook
      14.4.6. COMPANY6 Overview Financials Developments Strategic Outlook
      14.4.7. COMPANY7 Overview Financials Developments Strategic Outlook
      14.4.8. COMPANY8 Overview Financials Developments Strategic Outlook
      14.4.9. COMPANY9 Overview Financials Developments Strategic Outlook
      14.4.10. COMPANY 10 Overview Financials Developments Strategic Outlook
      14.4.11. COMPANY 11 Overview Financials Developments Strategic Outlook
      14.4.12. COMPANY 12 Overview Financials Developments Strategic Outlook
      14.4.13. COMPANY 13 Overview Financials Developments Strategic Outlook
      14.4.14. COMPANY 14 Overview Financials Developments Strategic Outlook
      14.4.15. COMPANY 15 Overview Financials Developments Strategic Outlook
      14.4.16. COMPANY 16 Overview Financials Developments Strategic Outlook
      14.4.17. COMPANY 17 Overview Financials Developments Strategic Outlook
      14.4.18. COMPANY 18 Overview Financials Developments Strategic Outlook
      14.4.19. COMPANY 19 Overview Financials Developments Strategic Outlook
      14.4.20. COMPANY 20 Overview Financials

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