Market Overview:
The global market for Mitogen Activated Protein Kinase 8 is expected to grow at a CAGR of xx% during the forecast period from 2018 to 2030. The growth in this market can be attributed to the increasing prevalence of chronic diseases, rising demand for targeted therapies, and growing investments in R&D. The global market for Mitogen Activated Protein Kinase 8 is segmented on the basis of type, application, and region. On the basis of type, the market is segmented into CC-90001, ER-358063, SR-3306 WBZ-4 Others). On the basis of application, the market is segmented into acute renal failure (ARF), breast cancer (BC), Alzheimer's disease (AD), liver failure (LF), and others). The regional segments are North America Latin America Europe Asia Pacific Middle East & Africa.
Product Definition:
Mitogen activated protein kinase 8 (MAPK8) is a member of the mitogen-activated protein kinase family. MAPK8 is also known as c-Jun N-terminal kinases (JNKs), and plays a role in cell signaling. JNK proteins are activated by exposure to environmental stressors, such as ultraviolet radiation, heat shock, and various chemicals. Once activated, JNKs phosphorylate their target proteins, including the transcription factor c-Jun.
CC-90001:
CC-90001 is a novel small molecule inhibitor for the MEK (mitogen-activated protein kinase) 8, which has shown potent anti-cancer activity in vitro and in vivo. The compound has been developed by Cipla Inc., an Indian generic pharmaceutical company. It received Orphan Drug Designation from the U.S FDA and Fast Track Designation from the European Medicines Agency (EMA).
ER-358063:
ER-358063 is a novel, Potent and selective inhibitor of MEK1/2 (but not PDK1) with IC 50 values of 1.0 ?M and 0.5?M respectively.
Application Insights:
The acute renal failure segment dominated the global mitogen-activated protein kinase 8 market in terms of revenue in 2017. This is attributed to a high incidence of this condition which requires immediate treatment with a kidney transplant or dialysis. Moreover, there are no available drugs that can cure this condition; therefore, patients suffering from it have to rely on treatment with enzyme replacement therapy or medications for short term relief only.
The breast cancer segment is expected to grow at the fastest rate during the forecast period owing to increasing awareness about early detection and rising prevalence rates globally. Breast cancer is one of the most common types of cancer found among women; however, it has very few symptoms and early diagnosis depends largely on female reproductive system examination by doctors.
Regional Analysis:
North America dominated the global market in 2017. The presence of a large number of manufacturers and suppliers, favorable reimbursement policies, and increasing healthcare expenditure are some factors contributing to the regional growth. For instance, in August 2016, Merck & Co., Inc., announced that it received FDA approval for its drug Keytruda (pembrolizumab) as an add-on treatment for patients with advanced non-small cell lung cancer (NSCLC). In October 2014, Bristol-Myers Squibb Company received FDA approval for Opdivo (nivolumab) as an add on therapy to standard chemotherapy in patients with unresectable liver metastases from sites including colon or rectal origin.
Growth Factors:
- Increasing prevalence of cancer and other diseases that are known to be associated with MAPK8 activation will continue to drive demand for MAPK8 inhibitors and therapies.
- Growing investment in R&D for new MAPK8 inhibitors and therapies will result in more products being brought to market, fueling growth of the MAPK8 market.
- increasing awareness among physicians and patients about the benefits of using MAPK8 inhibitors for the treatment of various diseases is expected to spur growth in this market over the forecast period.
Scope Of The Report
Report Attributes
Report Details
Report Title
Mitogen Activated Protein Kinase 8 Market Research Report
By Type
CC-90001, ER-358063, SR-3306, WBZ-4, Others
By Application
Acute Renal Failure, Breast Cancer, Alzheimer's Disease, Liver Failure, Others
By Companies
Celgene Corp, Eisai Co Ltd, OPKO Health Inc, Xigen SA, Celgene Corp
Regions Covered
North America, Europe, APAC, Latin America, MEA
Base Year
2021
Historical Year
2019 to 2020 (Data from 2010 can be provided as per availability)
Forecast Year
2030
Number of Pages
169
Number of Tables & Figures
119
Customization Available
Yes, the report can be customized as per your need.
Global Mitogen Activated Protein Kinase 8 Market Report Segments:
The global Mitogen Activated Protein Kinase 8 market is segmented on the basis of:
Types
CC-90001, ER-358063, SR-3306, WBZ-4, Others
The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.
Applications
Acute Renal Failure, Breast Cancer, Alzheimer's Disease, Liver Failure, Others
The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.
Some of the companies that are profiled in this report are:
- Celgene Corp
- Eisai Co Ltd
- OPKO Health Inc
- Xigen SA
- Celgene Corp
Highlights of The Mitogen Activated Protein Kinase 8 Market Report:
- The market structure and projections for the coming years.
- Drivers, restraints, opportunities, and current trends of market.
- Historical data and forecast.
- Estimations for the forecast period 2030.
- Developments and trends in the market.
- By Type:
- CC-90001
- ER-358063
- SR-3306
- WBZ-4
- Others
- By Application:
- Acute Renal Failure
- Breast Cancer
- Alzheimer's Disease
- Liver Failure
- Others
- Market scenario by region, sub-region, and country.
- Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
- Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
- Government Policies, Macro & Micro economic factors are also included in the report.
We have studied the Mitogen Activated Protein Kinase 8 Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.
Regional Analysis
- North America
- Europe
- Asia Pacific
- Middle East & Africa
- Latin America
Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.
The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.
How you may use our products:
- Correctly Positioning New Products
- Market Entry Strategies
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- Consumer Insights
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- Product & Brand Management
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8 Reasons to Buy This Report
- Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
- Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
- Implemented Robust Methodology to Prepare the Report
- Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
- Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
- Provides Information About the Top-winning Strategies Implemented by Industry Players.
- In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
- Customization of the Report Available
Frequently Asked Questions?
Mitogen Activated Protein Kinase 8 is a protein that helps to control the activity of other proteins. This protein is activated by various types of stress, such as exercise or infection, and helps to activate other proteins that can help to repair damage or fight off infections.
Some of the key players operating in the mitogen activated protein kinase 8 market are Celgene Corp, Eisai Co Ltd, OPKO Health Inc, Xigen SA, Celgene Corp.
Chapter 1 Executive Summary
Chapter 2 Assumptions and Acronyms Used
Chapter 3 Research Methodology
Chapter 4 Mitogen Activated Protein Kinase 8 Market Overview
4.1 Introduction
4.1.1 Market Taxonomy
4.1.2 Market Definition
4.1.3 Macro-Economic Factors Impacting the Market Growth
4.2 Mitogen Activated Protein Kinase 8 Market Dynamics
4.2.1 Market Drivers
4.2.2 Market Restraints
4.2.3 Market Opportunity
4.3 Mitogen Activated Protein Kinase 8 Market - Supply Chain Analysis
4.3.1 List of Key Suppliers
4.3.2 List of Key Distributors
4.3.3 List of Key Consumers
4.4 Key Forces Shaping the Mitogen Activated Protein Kinase 8 Market
4.4.1 Bargaining Power of Suppliers
4.4.2 Bargaining Power of Buyers
4.4.3 Threat of Substitution
4.4.4 Threat of New Entrants
4.4.5 Competitive Rivalry
4.5 Global Mitogen Activated Protein Kinase 8 Market Size & Forecast, 2020-2028
4.5.1 Mitogen Activated Protein Kinase 8 Market Size and Y-o-Y Growth
4.5.2 Mitogen Activated Protein Kinase 8 Market Absolute $ Opportunity
Chapter 5 Global Market Analysis and Forecast by Type
5.1 Introduction
5.1.1 Key Market Trends & Growth Opportunities by Type
5.1.2 Basis Point Share (BPS) Analysis by Type
5.1.3 Absolute $ Opportunity Assessment by Type
5.2 Market Size Forecast by Type
5.2.1 CC-90001
5.2.2 ER-358063
5.2.3 SR-3306
5.2.4 WBZ-4
5.2.5 Others
5.3 Market Attractiveness Analysis by Type
Chapter 6 Global Market Analysis and Forecast by Applications
6.1 Introduction
6.1.1 Key Market Trends & Growth Opportunities by Applications
6.1.2 Basis Point Share (BPS) Analysis by Applications
6.1.3 Absolute $ Opportunity Assessment by Applications
6.2 Market Size Forecast by Applications
6.2.1 Acute Renal Failure
6.2.2 Breast Cancer
6.2.3 Alzheimer's Disease
6.2.4 Liver Failure
6.2.5 Others
6.3 Market Attractiveness Analysis by Applications
Chapter 7 Global Mitogen Activated Protein Kinase 8 Market Analysis and Forecast by Region
7.1 Introduction
7.1.1 Key Market Trends & Growth Opportunities by Region
7.1.2 Basis Point Share (BPS) Analysis by Region
7.1.3 Absolute $ Opportunity Assessment by Region
7.2 Mitogen Activated Protein Kinase 8 Market Size Forecast by Region
7.2.1 North America
7.2.2 Europe
7.2.3 Asia Pacific
7.2.4 Latin America
7.2.5 Middle East & Africa (MEA)
7.3 Market Attractiveness Analysis by Region
Chapter 8 Coronavirus Disease (COVID-19) Impact
8.1 Introduction
8.2 Current & Future Impact Analysis
8.3 Economic Impact Analysis
8.4 Government Policies
8.5 Investment Scenario
Chapter 9 North America Analysis and Forecast
9.1 Introduction
9.2 North America Market Size Forecast by Country
9.2.1 U.S.
9.2.2 Canada
9.3 Basis Point Share (BPS) Analysis by Country
9.4 Absolute $ Opportunity Assessment by Country
9.5 Market Attractiveness Analysis by Country
9.6 North America Market Size Forecast by Type
9.6.1 CC-90001
9.6.2 ER-358063
9.6.3 SR-3306
9.6.4 WBZ-4
9.6.5 Others
9.7 Basis Point Share (BPS) Analysis by Type
9.8 Absolute $ Opportunity Assessment by Type
9.9 Market Attractiveness Analysis by Type
9.10 North America Market Size Forecast by Applications
9.10.1 Acute Renal Failure
9.10.2 Breast Cancer
9.10.3 Alzheimer's Disease
9.10.4 Liver Failure
9.10.5 Others
9.11 Basis Point Share (BPS) Analysis by Applications
9.12 Absolute $ Opportunity Assessment by Applications
9.13 Market Attractiveness Analysis by Applications
Chapter 10 Europe Analysis and Forecast
10.1 Introduction
10.2 Europe Market Size Forecast by Country
10.2.1 Germany
10.2.2 France
10.2.3 Italy
10.2.4 U.K.
10.2.5 Spain
10.2.6 Russia
10.2.7 Rest of Europe
10.3 Basis Point Share (BPS) Analysis by Country
10.4 Absolute $ Opportunity Assessment by Country
10.5 Market Attractiveness Analysis by Country
10.6 Europe Market Size Forecast by Type
10.6.1 CC-90001
10.6.2 ER-358063
10.6.3 SR-3306
10.6.4 WBZ-4
10.6.5 Others
10.7 Basis Point Share (BPS) Analysis by Type
10.8 Absolute $ Opportunity Assessment by Type
10.9 Market Attractiveness Analysis by Type
10.10 Europe Market Size Forecast by Applications
10.10.1 Acute Renal Failure
10.10.2 Breast Cancer
10.10.3 Alzheimer's Disease
10.10.4 Liver Failure
10.10.5 Others
10.11 Basis Point Share (BPS) Analysis by Applications
10.12 Absolute $ Opportunity Assessment by Applications
10.13 Market Attractiveness Analysis by Applications
Chapter 11 Asia Pacific Analysis and Forecast
11.1 Introduction
11.2 Asia Pacific Market Size Forecast by Country
11.2.1 China
11.2.2 Japan
11.2.3 South Korea
11.2.4 India
11.2.5 Australia
11.2.6 South East Asia (SEA)
11.2.7 Rest of Asia Pacific (APAC)
11.3 Basis Point Share (BPS) Analysis by Country
11.4 Absolute $ Opportunity Assessment by Country
11.5 Market Attractiveness Analysis by Country
11.6 Asia Pacific Market Size Forecast by Type
11.6.1 CC-90001
11.6.2 ER-358063
11.6.3 SR-3306
11.6.4 WBZ-4
11.6.5 Others
11.7 Basis Point Share (BPS) Analysis by Type
11.8 Absolute $ Opportunity Assessment by Type
11.9 Market Attractiveness Analysis by Type
11.10 Asia Pacific Market Size Forecast by Applications
11.10.1 Acute Renal Failure
11.10.2 Breast Cancer
11.10.3 Alzheimer's Disease
11.10.4 Liver Failure
11.10.5 Others
11.11 Basis Point Share (BPS) Analysis by Applications
11.12 Absolute $ Opportunity Assessment by Applications
11.13 Market Attractiveness Analysis by Applications
Chapter 12 Latin America Analysis and Forecast
12.1 Introduction
12.2 Latin America Market Size Forecast by Country
12.2.1 Brazil
12.2.2 Mexico
12.2.3 Rest of Latin America (LATAM)
12.3 Basis Point Share (BPS) Analysis by Country
12.4 Absolute $ Opportunity Assessment by Country
12.5 Market Attractiveness Analysis by Country
12.6 Latin America Market Size Forecast by Type
12.6.1 CC-90001
12.6.2 ER-358063
12.6.3 SR-3306
12.6.4 WBZ-4
12.6.5 Others
12.7 Basis Point Share (BPS) Analysis by Type
12.8 Absolute $ Opportunity Assessment by Type
12.9 Market Attractiveness Analysis by Type
12.10 Latin America Market Size Forecast by Applications
12.10.1 Acute Renal Failure
12.10.2 Breast Cancer
12.10.3 Alzheimer's Disease
12.10.4 Liver Failure
12.10.5 Others
12.11 Basis Point Share (BPS) Analysis by Applications
12.12 Absolute $ Opportunity Assessment by Applications
12.13 Market Attractiveness Analysis by Applications
Chapter 13 Middle East & Africa (MEA) Analysis and Forecast
13.1 Introduction
13.2 Middle East & Africa (MEA) Market Size Forecast by Country
13.2.1 Saudi Arabia
13.2.2 South Africa
13.2.3 UAE
13.2.4 Rest of Middle East & Africa (MEA)
13.3 Basis Point Share (BPS) Analysis by Country
13.4 Absolute $ Opportunity Assessment by Country
13.5 Market Attractiveness Analysis by Country
13.6 Middle East & Africa (MEA) Market Size Forecast by Type
13.6.1 CC-90001
13.6.2 ER-358063
13.6.3 SR-3306
13.6.4 WBZ-4
13.6.5 Others
13.7 Basis Point Share (BPS) Analysis by Type
13.8 Absolute $ Opportunity Assessment by Type
13.9 Market Attractiveness Analysis by Type
13.10 Middle East & Africa (MEA) Market Size Forecast by Applications
13.10.1 Acute Renal Failure
13.10.2 Breast Cancer
13.10.3 Alzheimer's Disease
13.10.4 Liver Failure
13.10.5 Others
13.11 Basis Point Share (BPS) Analysis by Applications
13.12 Absolute $ Opportunity Assessment by Applications
13.13 Market Attractiveness Analysis by Applications
Chapter 14 Competition Landscape
14.1 Mitogen Activated Protein Kinase 8 Market: Competitive Dashboard
14.2 Global Mitogen Activated Protein Kinase 8 Market: Market Share Analysis, 2019
14.3 Company Profiles (Details – Overview, Financials, Developments, Strategy)
14.3.1 Celgene Corp
14.3.2 Eisai Co Ltd
14.3.3 OPKO Health Inc
14.3.4 Xigen SA
14.3.5 Celgene Corp
