Market Overview:
The global rho associated protein kinase 1 market is expected to grow at a CAGR of xx% during the forecast period from 2018 to 2030. The growth in this market can be attributed to the increasing prevalence of various diseases, rising geriatric population, and growing demand for novel therapeutics. Based on type, the global rho associated protein kinase 1 market is segmented into AN-3485, KL-01045, AT-13148, TRX-101 and others. The KL-01045 segment is expected to account for the largest share of the global rho associated protein kinase 1 market in 2018. This segment is also projected to grow at a CAGR of xx% during the forecast period from 2018 to 2030. Based on application, the global rho associated protein kinase 1 market is divided into central nervous system (CNS), contact dermatitis (CD), fibrosis and others. The CNS segment accounted for majority share of this market in 2017 and it is projected that this trend will continue duringthe forecast period from2018to2030 owing tobethe high prevalenceof CNS disorders such as Alzheimer’s diseaseand Parkinson’sdiseases across different regions worldwide.
Product Definition:
Rho Associated Protein Kinase 1 is a protein that helps to regulate the activity of other proteins by phosphorylating them. It is important for cell movement, proliferation, and differentiation.
AN-3485:
AN-3485 is a selective inhibitor of Rho-associated coiled-coil kinase 1 (ROCK1). It has been studied in combination with other drugs for the treatment of various cancers. The drug has shown efficacy and safety in Phase II clinical trials, which have led to its approval by the U.S. FDA as a second line therapy for patients who cannot tolerate sunitinib malate or whose cancer progressed after sunitinib treatment.
KL-01045:
KL-01045 is a selective inhibitor of Rho-associated protein kinase 1 (ROCK1). ROCK1 is one of the key enzymes involved in the cellular response to stress including cell growth, apoptosis, and DNA repair.
Application Insights:
The central nervous system segment dominated the global market in 2017. This is due to the presence of a large number of products for treating CNS disorders, such as RAP1 inhibitor (Zolpidem), anesthetic (Halofantrine), and anticonvulsant. Moreover, increasing incidences of brain injuries are expected to boost product demand over the forecast period. Contact dermatitis segment is also expected to grow at lucrative rate during the study period owing to rising awareness about skin diseases and increased product penetration for treatment.
Rapid growth in fibrosis market can be attributed towards growing incidence rates of chronic kidney disease (CKD) coupled with rising awareness about associated protein kinases 1 & 2 enzymes activities that play a major role in CKD progression and management.
Regional Analysis:
North America dominated the global market in 2017. The presence of a large number of key players and high adoption rate for cosmetic products are some factors responsible for its largest share. In addition, increasing RAPK1-associated diseases such as multiple sclerosis, scleroderma, and arthritis is also expected to drive the regional growth over the forecast period.
Asia Pacific is expected to grow at a lucrative rate during the forecast period owing to rising disposable income coupled with growing awareness about early diagnosis in countries such as China and India. Moreover, an increase in investments by major pharmaceutical companies will boost market development further driving growth across this region particularly in Japan and South Korea over next eight years from 2018 to 2030 time frame).
In 2016 Novartis AG invested around USD X million for research on chronic inflammatory diseases that are associated with Rho proteins which include rheumatoid arthritis & psoriasis among others (Novartis 2016).
Growth Factors:
- Increasing prevalence of cancer: The increasing prevalence of cancer is one of the key growth drivers for the Rho Associated Protein Kinase 1 market. According to the World Health Organization, in 2012, there were 14 million new cases of cancer and 8.2 million deaths due to cancer worldwide. This number is expected to increase to 21 million new cases and 13 million deaths by 2030. This will create a high demand for Rho Associated Protein Kinase 1 products and services, thereby driving the market growth.
- Rising awareness about early diagnosis and treatment: There is an increasing awareness among people about early diagnosis and treatment of cancers. This has led to an increase in the demand for diagnostic tests and therapies such as those involving Rho Associated Protein Kinase 1 products. This will drive market growth in the coming years.
Scope Of The Report
Report Attributes
Report Details
Report Title
Rho Associated Protein Kinase 1 Market Research Report
By Type
AN-3485, KL-01045, AT-13148, TRX-101, Others
By Application
Central Nervous System, Contact Dermatitis, Fibrosis, Others
By Companies
AbbVie Inc, Astex Pharmaceuticals Inc, BioAxone BioSciences Inc, Kadmon Corp LLC, Pfizer Inc, Redx Pharma Plc
Regions Covered
North America, Europe, APAC, Latin America, MEA
Base Year
2021
Historical Year
2019 to 2020 (Data from 2010 can be provided as per availability)
Forecast Year
2030
Number of Pages
239
Number of Tables & Figures
168
Customization Available
Yes, the report can be customized as per your need.
Global Rho Associated Protein Kinase 1 Market Report Segments:
The global Rho Associated Protein Kinase 1 market is segmented on the basis of:
Types
AN-3485, KL-01045, AT-13148, TRX-101, Others
The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.
Applications
Central Nervous System, Contact Dermatitis, Fibrosis, Others
The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.
Some of the companies that are profiled in this report are:
- AbbVie Inc
- Astex Pharmaceuticals Inc
- BioAxone BioSciences Inc
- Kadmon Corp LLC
- Pfizer Inc
- Redx Pharma Plc
Highlights of The Rho Associated Protein Kinase 1 Market Report:
- The market structure and projections for the coming years.
- Drivers, restraints, opportunities, and current trends of market.
- Historical data and forecast.
- Estimations for the forecast period 2030.
- Developments and trends in the market.
- By Type:
- AN-3485
- KL-01045
- AT-13148
- TRX-101
- Others
- By Application:
- Central Nervous System
- Contact Dermatitis
- Fibrosis
- Others
- Market scenario by region, sub-region, and country.
- Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
- Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
- Government Policies, Macro & Micro economic factors are also included in the report.
We have studied the Rho Associated Protein Kinase 1 Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.
Regional Analysis
- North America
- Europe
- Asia Pacific
- Middle East & Africa
- Latin America
Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.
The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.
How you may use our products:
- Correctly Positioning New Products
- Market Entry Strategies
- Business Expansion Strategies
- Consumer Insights
- Understanding Competition Scenario
- Product & Brand Management
- Channel & Customer Management
- Identifying Appropriate Advertising Appeals
8 Reasons to Buy This Report
- Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
- Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
- Implemented Robust Methodology to Prepare the Report
- Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
- Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
- Provides Information About the Top-winning Strategies Implemented by Industry Players.
- In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
- Customization of the Report Available
Frequently Asked Questions?
Rho Associated Protein Kinase 1 (ROCK1) is an enzyme that phosphorylates proteins. ROCK1 is activated by the Rho family of GTPases and can phosphorylate a wide variety of proteins, including those involved in cell motility, signal transduction, and transcription. Phosphorylation of ROCK1 can regulate its activity and influence cellular processes.
Some of the major players in the rho associated protein kinase 1 market are AbbVie Inc, Astex Pharmaceuticals Inc, BioAxone BioSciences Inc, Kadmon Corp LLC, Pfizer Inc, Redx Pharma Plc.
Chapter 1 Executive Summary
Chapter 2 Assumptions and Acronyms Used
Chapter 3 Research Methodology
Chapter 4 Rho Associated Protein Kinase 1 Market Overview
4.1 Introduction
4.1.1 Market Taxonomy
4.1.2 Market Definition
4.1.3 Macro-Economic Factors Impacting the Market Growth
4.2 Rho Associated Protein Kinase 1 Market Dynamics
4.2.1 Market Drivers
4.2.2 Market Restraints
4.2.3 Market Opportunity
4.3 Rho Associated Protein Kinase 1 Market - Supply Chain Analysis
4.3.1 List of Key Suppliers
4.3.2 List of Key Distributors
4.3.3 List of Key Consumers
4.4 Key Forces Shaping the Rho Associated Protein Kinase 1 Market
4.4.1 Bargaining Power of Suppliers
4.4.2 Bargaining Power of Buyers
4.4.3 Threat of Substitution
4.4.4 Threat of New Entrants
4.4.5 Competitive Rivalry
4.5 Global Rho Associated Protein Kinase 1 Market Size & Forecast, 2018-2028
4.5.1 Rho Associated Protein Kinase 1 Market Size and Y-o-Y Growth
4.5.2 Rho Associated Protein Kinase 1 Market Absolute $ Opportunity
Chapter 5 Global Rho Associated Protein Kinase 1 Market Analysis and Forecast by Type
5.1 Introduction
5.1.1 Key Market Trends & Growth Opportunities by Type
5.1.2 Basis Point Share (BPS) Analysis by Type
5.1.3 Absolute $ Opportunity Assessment by Type
5.2 Rho Associated Protein Kinase 1 Market Size Forecast by Type
5.2.1 AN-3485
5.2.2 KL-01045
5.2.3 AT-13148
5.2.4 TRX-101
5.2.5 Others
5.3 Market Attractiveness Analysis by Type
Chapter 6 Global Rho Associated Protein Kinase 1 Market Analysis and Forecast by Applications
6.1 Introduction
6.1.1 Key Market Trends & Growth Opportunities by Applications
6.1.2 Basis Point Share (BPS) Analysis by Applications
6.1.3 Absolute $ Opportunity Assessment by Applications
6.2 Rho Associated Protein Kinase 1 Market Size Forecast by Applications
6.2.1 Central Nervous System
6.2.2 Contact Dermatitis
6.2.3 Fibrosis
6.2.4 Others
6.3 Market Attractiveness Analysis by Applications
Chapter 7 Global Rho Associated Protein Kinase 1 Market Analysis and Forecast by Region
7.1 Introduction
7.1.1 Key Market Trends & Growth Opportunities by Region
7.1.2 Basis Point Share (BPS) Analysis by Region
7.1.3 Absolute $ Opportunity Assessment by Region
7.2 Rho Associated Protein Kinase 1 Market Size Forecast by Region
7.2.1 North America
7.2.2 Europe
7.2.3 Asia Pacific
7.2.4 Latin America
7.2.5 Middle East & Africa (MEA)
7.3 Market Attractiveness Analysis by Region
Chapter 8 Coronavirus Disease (COVID-19) Impact
8.1 Introduction
8.2 Current & Future Impact Analysis
8.3 Economic Impact Analysis
8.4 Government Policies
8.5 Investment Scenario
Chapter 9 North America Rho Associated Protein Kinase 1 Analysis and Forecast
9.1 Introduction
9.2 North America Rho Associated Protein Kinase 1 Market Size Forecast by Country
9.2.1 U.S.
9.2.2 Canada
9.3 Basis Point Share (BPS) Analysis by Country
9.4 Absolute $ Opportunity Assessment by Country
9.5 Market Attractiveness Analysis by Country
9.6 North America Rho Associated Protein Kinase 1 Market Size Forecast by Type
9.6.1 AN-3485
9.6.2 KL-01045
9.6.3 AT-13148
9.6.4 TRX-101
9.6.5 Others
9.7 Basis Point Share (BPS) Analysis by Type
9.8 Absolute $ Opportunity Assessment by Type
9.9 Market Attractiveness Analysis by Type
9.10 North America Rho Associated Protein Kinase 1 Market Size Forecast by Applications
9.10.1 Central Nervous System
9.10.2 Contact Dermatitis
9.10.3 Fibrosis
9.10.4 Others
9.11 Basis Point Share (BPS) Analysis by Applications
9.12 Absolute $ Opportunity Assessment by Applications
9.13 Market Attractiveness Analysis by Applications
Chapter 10 Europe Rho Associated Protein Kinase 1 Analysis and Forecast
10.1 Introduction
10.2 Europe Rho Associated Protein Kinase 1 Market Size Forecast by Country
10.2.1 Germany
10.2.2 France
10.2.3 Italy
10.2.4 U.K.
10.2.5 Spain
10.2.6 Russia
10.2.7 Rest of Europe
10.3 Basis Point Share (BPS) Analysis by Country
10.4 Absolute $ Opportunity Assessment by Country
10.5 Market Attractiveness Analysis by Country
10.6 Europe Rho Associated Protein Kinase 1 Market Size Forecast by Type
10.6.1 AN-3485
10.6.2 KL-01045
10.6.3 AT-13148
10.6.4 TRX-101
10.6.5 Others
10.7 Basis Point Share (BPS) Analysis by Type
10.8 Absolute $ Opportunity Assessment by Type
10.9 Market Attractiveness Analysis by Type
10.10 Europe Rho Associated Protein Kinase 1 Market Size Forecast by Applications
10.10.1 Central Nervous System
10.10.2 Contact Dermatitis
10.10.3 Fibrosis
10.10.4 Others
10.11 Basis Point Share (BPS) Analysis by Applications
10.12 Absolute $ Opportunity Assessment by Applications
10.13 Market Attractiveness Analysis by Applications
Chapter 11 Asia Pacific Rho Associated Protein Kinase 1 Analysis and Forecast
11.1 Introduction
11.2 Asia Pacific Rho Associated Protein Kinase 1 Market Size Forecast by Country
11.2.1 China
11.2.2 Japan
11.2.3 South Korea
11.2.4 India
11.2.5 Australia
11.2.6 South East Asia (SEA)
11.2.7 Rest of Asia Pacific (APAC)
11.3 Basis Point Share (BPS) Analysis by Country
11.4 Absolute $ Opportunity Assessment by Country
11.5 Market Attractiveness Analysis by Country
11.6 Asia Pacific Rho Associated Protein Kinase 1 Market Size Forecast by Type
11.6.1 AN-3485
11.6.2 KL-01045
11.6.3 AT-13148
11.6.4 TRX-101
11.6.5 Others
11.7 Basis Point Share (BPS) Analysis by Type
11.8 Absolute $ Opportunity Assessment by Type
11.9 Market Attractiveness Analysis by Type
11.10 Asia Pacific Rho Associated Protein Kinase 1 Market Size Forecast by Applications
11.10.1 Central Nervous System
11.10.2 Contact Dermatitis
11.10.3 Fibrosis
11.10.4 Others
11.11 Basis Point Share (BPS) Analysis by Applications
11.12 Absolute $ Opportunity Assessment by Applications
11.13 Market Attractiveness Analysis by Applications
Chapter 12 Latin America Rho Associated Protein Kinase 1 Analysis and Forecast
12.1 Introduction
12.2 Latin America Rho Associated Protein Kinase 1 Market Size Forecast by Country
12.2.1 Brazil
12.2.2 Mexico
12.2.3 Rest of Latin America (LATAM)
12.3 Basis Point Share (BPS) Analysis by Country
12.4 Absolute $ Opportunity Assessment by Country
12.5 Market Attractiveness Analysis by Country
12.6 Latin America Rho Associated Protein Kinase 1 Market Size Forecast by Type
12.6.1 AN-3485
12.6.2 KL-01045
12.6.3 AT-13148
12.6.4 TRX-101
12.6.5 Others
12.7 Basis Point Share (BPS) Analysis by Type
12.8 Absolute $ Opportunity Assessment by Type
12.9 Market Attractiveness Analysis by Type
12.10 Latin America Rho Associated Protein Kinase 1 Market Size Forecast by Applications
12.10.1 Central Nervous System
12.10.2 Contact Dermatitis
12.10.3 Fibrosis
12.10.4 Others
12.11 Basis Point Share (BPS) Analysis by Applications
12.12 Absolute $ Opportunity Assessment by Applications
12.13 Market Attractiveness Analysis by Applications
Chapter 13 Middle East & Africa (MEA) Rho Associated Protein Kinase 1 Analysis and Forecast
13.1 Introduction
13.2 Middle East & Africa (MEA) Rho Associated Protein Kinase 1 Market Size Forecast by Country
13.2.1 Saudi Arabia
13.2.2 South Africa
13.2.3 UAE
13.2.4 Rest of Middle East & Africa (MEA)
13.3 Basis Point Share (BPS) Analysis by Country
13.4 Absolute $ Opportunity Assessment by Country
13.5 Market Attractiveness Analysis by Country
13.6 Middle East & Africa (MEA) Rho Associated Protein Kinase 1 Market Size Forecast by Type
13.6.1 AN-3485
13.6.2 KL-01045
13.6.3 AT-13148
13.6.4 TRX-101
13.6.5 Others
13.7 Basis Point Share (BPS) Analysis by Type
13.8 Absolute $ Opportunity Assessment by Type
13.9 Market Attractiveness Analysis by Type
13.10 Middle East & Africa (MEA) Rho Associated Protein Kinase 1 Market Size Forecast by Applications
13.10.1 Central Nervous System
13.10.2 Contact Dermatitis
13.10.3 Fibrosis
13.10.4 Others
13.11 Basis Point Share (BPS) Analysis by Applications
13.12 Absolute $ Opportunity Assessment by Applications
13.13 Market Attractiveness Analysis by Applications
Chapter 14 Competition Landscape
14.1 Rho Associated Protein Kinase 1 Market: Competitive Dashboard
14.2 Global Rho Associated Protein Kinase 1 Market: Market Share Analysis, 2019
14.3 Company Profiles (Details – Overview, Financials, Developments, Strategy)
14.3.1 AbbVie Inc
14.3.2 Astex Pharmaceuticals Inc
14.3.3 BioAxone BioSciences Inc
14.3.4 Kadmon Corp LLC
14.3.5 Pfizer Inc
14.3.6 Redx Pharma Plc
