Latest Update: Impact of current COVID-19 situation has been considered in this report while making the analysis.
Global HEPES Market by Type (Crystalline Powder, Buffering Agent), By Application (Cell Culture, Protein Extraction, Others) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030-report

Global HEPES Market by Type (Crystalline Powder, Buffering Agent), By Application (Cell Culture, Protein Extraction, Others) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030

Report ID: 138271 3300 Chemical & Material 377 231 Pages 5 (33)

Market Overview:

The global HEPES market is expected to grow at a CAGR of 5.5% during the forecast period from 2018 to 2030. The growth in the market can be attributed to the increasing demand for HEPES in cell culture and protein extraction applications. Additionally, rising research and development expenditure by pharmaceutical and biotechnology companies is also propelling the growth of the global HEPES market. However, stringent regulatory norms for drug approvals are restraining the growth of this market to some extent.

Global HEPES Industry Outlook

Product Definition:

A salt that is used to keep cells alive in a laboratory dish. It is important because it helps to maintain the right balance of acid and base in the cells' environment.

Crystalline Powder:

Crystalline powder is a solid form of salts which are made up of individual crystals. It has wide applications in the chemical industry and finds major use in pH control, deionization, evaporation processes and as an electrolyte. Crystalline powder is also used as a carrier for other chemicals or drugs by melting it down before adding to solutions that require cooling or heating purposes.

Buffering Agent:

A buffering agent is a substance that delays the reaction between two compounds by creating an environment that is more stable. The most common example of such agents are salts and alkalis used in pH buffers. Buffering agents can also be organic acids or bases, for instance, lactic acid helps to maintain the pH levels in muscle cells and blood; while bicarbonate (HCO3) acts as an antacid to prevent stomach irritation.

Application Insights:

Protein extraction was the largest application segment in terms of revenue and is expected to witness a CAGR of XX% from 2018 to 2030. The growth can be attributed to increasing demand for protein isolation from various sources such as human blood, tissue culture, milk powder, egg white powder and other animal sources.

The others segment includes chemical synthesis and is estimated to witness volume growth at a CAGR of XX% over the forecast period owing to rising demand for HEPES salts in various applications including glass manufacturing, paper making.

Regional Analysis:

North America dominated the global market in terms of revenue with a share of over 40.0% in 2017. This is attributed to the presence of major pharmaceutical and biopharmaceutical companies, which are engaged in R&D activities for new drug development and other therapeutic applications at high energy density phosphate compounds. Moreover, increasing government funding for research activities pertaining to hydration properties of drugs will further boost growth during the forecast period from 2018 to 2030.

Asia Pacific is expected to witness lucrative growth over the coming years owing to rising investments by leading pharmaceutical companies such as Gilead Sciences, FUJIFILM Diosynth Biotechnologies Corporation, Novartis AG., among others for product development and research purposes related to hydrophilic properties associated with hydroxyapatite-based products used across various industries including healthcare & life sciences (HLS).

Growth Factors:

  • Increasing demand for biotechnology and pharmaceutical products
  • Rising prevalence of chronic diseases
  • Growing number of research and development activities in the life sciences sector
  • Technological advancements in the field of biochemistry
  • Rising awareness about health and hygiene among consumers

Scope Of The Report

Report Attributes

Report Details

Report Title

HEPES Market Research Report

By Type

Crystalline Powder, Buffering Agent

By Application

Cell Culture, Protein Extraction, Others

By Companies

Merck KGaA, Formedium, Amresco, Thermo Fisher Scientific, Caisson, Lonza, Ge Healthcare, Biological Industries, Cayman Chemical, SERVA Electrophoresis GmbH, Tocris Bioscience, BioSpectra, Avantor, VWR International, Corning, Irvine

Regions Covered

North America, Europe, APAC, Latin America, MEA

Base Year


Historical Year

2019 to 2020 (Data from 2010 can be provided as per availability)

Forecast Year


Number of Pages


Number of Tables & Figures


Customization Available

Yes, the report can be customized as per your need.

Global HEPES Market Report Segments:

The global HEPES market is segmented on the basis of:


Crystalline Powder, Buffering Agent

The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.


Cell Culture, Protein Extraction, Others

The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.

Some of the companies that are profiled in this report are:

  1. Merck KGaA
  2. Formedium
  3. Amresco
  4. Thermo Fisher Scientific
  5. Caisson
  6. Lonza
  7. Ge Healthcare
  8. Biological Industries
  9. Cayman Chemical
  10. SERVA Electrophoresis GmbH
  11. Tocris Bioscience
  12. BioSpectra
  13. Avantor
  14. VWR International
  15. Corning
  16. Irvine

Global HEPES Market Overview

Highlights of The HEPES Market Report:

  1. The market structure and projections for the coming years.
  2. Drivers, restraints, opportunities, and current trends of market.
  3. Historical data and forecast.
  4. Estimations for the forecast period 2030.
  5. Developments and trends in the market.
  6. By Type:

    1. Crystalline Powder
    2. Buffering Agent
  1. By Application:

    1. Cell Culture
    2. Protein Extraction
    3. Others
  1. Market scenario by region, sub-region, and country.
  2. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
  3. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
  4. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the HEPES Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.

Regional Analysis

  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.

The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.

How you may use our products:

  • Correctly Positioning New Products
  • Market Entry Strategies
  • Business Expansion Strategies
  • Consumer Insights
  • Understanding Competition Scenario
  • Product & Brand Management
  • Channel & Customer Management
  • Identifying Appropriate Advertising Appeals

Global HEPES Market Statistics

8 Reasons to Buy This Report

  1. Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
  2. Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
  3. Implemented Robust Methodology to Prepare the Report
  4. Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
  5. Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
  6. Provides Information About the Top-winning Strategies Implemented by Industry Players.
  7. In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
  8. Customization of the Report Available

Frequently Asked Questions?

HEPES is a common name for a molecule with the formula H3O4. It is an ionic compound, meaning that it consists of atoms of hydrogen and oxygen.

Some of the key players operating in the hepes market are Merck KGaA, Formedium, Amresco, Thermo Fisher Scientific, Caisson, Lonza, Ge Healthcare, Biological Industries, Cayman Chemical, SERVA Electrophoresis GmbH, Tocris Bioscience, BioSpectra, Avantor, VWR International, Corning, Irvine.

The hepes market is expected to grow at a compound annual growth rate of 5.5%.

1. Executive Summary

2. Assumptions and Acronyms Used

3. Research Methodology

4. HEPES Market Overview
   4.1. Introduction
      4.1.1. Market Taxonomy
      4.1.2. Market Definition
   4.2. Macro-Economic Factors
      4.2.1. Industry Outlook
   4.3. HEPES Market Dynamics
      4.3.1. Market Drivers
      4.3.2. Market Restraints
      4.3.3. Opportunity
      4.3.4. Market Trends
   4.4. HEPES Market - Supply Chain
   4.5. Global HEPES Market Forecast
      4.5.1. HEPES Market Size (US$ Mn) and Y-o-Y Growth
      4.5.2. HEPES Market Size (000’ Units) and Y-o-Y Growth
      4.5.3. HEPES Market Absolute $ Opportunity

5. Global HEPES Market Analysis and Forecast by Type
   5.1. Market Trends
   5.2. Introduction
      5.2.1. Basis Point Share (BPS) Analysis by Type
      5.2.2. Y-o-Y Growth Projections by Type
   5.3. HEPES Market Size and Volume Forecast by Type
      5.3.1. Crystalline Powder
      5.3.2. Buffering Agent
   5.4. Absolute $ Opportunity Assessment by Type
   5.5. Market Attractiveness/Growth Potential Analysis by Type

6. Global HEPES Market Analysis and Forecast by Application
   6.1. Market Trends
   6.2. Introduction
      6.2.1. Basis Point Share (BPS) Analysis by Application
      6.2.2. Y-o-Y Growth Projections by Application
   6.3. HEPES Market Size and Volume Forecast by Application
      6.3.1. Cell Culture
      6.3.2. Protein Extraction
      6.3.3. Others
   6.4. Absolute $ Opportunity Assessment by Application
   6.5. Market Attractiveness/Growth Potential Analysis by Application

7. Global HEPES Market Analysis and Forecast by Sales Channel
   7.1. Market Trends
   7.2. Introduction
      7.2.1. Basis Point Share (BPS) Analysis by Sales Channel 
      7.2.2. Y-o-Y Growth Projections by Sales Channel
   7.3. HEPES Market Size and Volume Forecast by Sales Channel 
      7.3.1. Manufacturer/Distributor/Service Provider
      7.3.2. Aftermarket
   7.4. Absolute $ Opportunity Assessment by Sales Channel
   7.5. Market Attractiveness/Growth Potential Analysis by Sales Channel

8. Global HEPES Market Analysis and Forecast by Region
   8.1. Market Trends
   8.2. Introduction
      8.2.1. Basis Point Share (BPS) Analysis by Region
      8.2.2. Y-o-Y Growth Projections by Region
   8.3. HEPES Market Size and Volume Forecast by Region
      8.3.1. North America
      8.3.2. Latin America
      8.3.3. Europe
      8.3.4. Asia Pacific
      8.3.5. Middle East and Africa (MEA)
   8.4. Absolute $ Opportunity Assessment by Region
   8.5. Market Attractiveness/Growth Potential Analysis by Region
   8.6. Global HEPES Demand Share Forecast, 2019-2029

9. North America HEPES Market Analysis and Forecast
   9.1. Introduction
      9.1.1. Basis Point Share (BPS) Analysis by Country
      9.1.2. Y-o-Y Growth Projections by Country
   9.2. North America HEPES Market Size and Volume Forecast by Country
      9.2.1. U.S.
      9.2.2. Canada
   9.3. Absolute $ Opportunity Assessment by Country
   9.4. North America HEPES Market Size and Volume Forecast by Application
      9.4.1. Cell Culture
      9.4.2. Protein Extraction
      9.4.3. Others
   9.5. Basis Point Share (BPS) Analysis by Application
   9.6. Y-o-Y Growth Projections by Application
   9.7. North America HEPES Market Size and Volume Forecast by Type
      9.7.1. Crystalline Powder
      9.7.2. Buffering Agent
   9.8. Basis Point Share (BPS) Analysis by Type
   9.9. Y-o-Y Growth Projections by Type
   9.10. Market Attractiveness/Growth Potential Analysis
      9.10.1. By Country
      9.10.2. By Product Type
      9.10.3. By Application
      9.10.4. By Sales Channel
   9.11. North America HEPES Demand Share Forecast, 2019-2029

10. Latin America HEPES Market Analysis and Forecast
   10.1. Introduction
      10.1.1. Basis Point Share (BPS) Analysis by Country
      10.1.2. Y-o-Y Growth Projections by Country
      10.1.3. Latin America Average Pricing Analysis
   10.2. Latin America HEPES Market Size and Volume Forecast by Country
      10.2.1. Brazil
      10.2.2. Mexico
      10.2.3. Rest of Latin America
   10.3. Absolute $ Opportunity Assessment by Country
   10.4. Latin America HEPES Market Size and Volume Forecast by Application
      10.4.1. Cell Culture
      10.4.2. Protein Extraction
      10.4.3. Others
   10.5. Basis Point Share (BPS) Analysis by Application
   10.6. Y-o-Y Growth Projections by Application
   10.7. Latin America HEPES Market Size and Volume Forecast by Type
      10.7.1. Crystalline Powder
      10.7.2. Buffering Agent
   10.8. Basis Point Share (BPS) Analysis by Type
   10.9. Y-o-Y Growth Projections by Type
   10.10. Market Attractiveness/Growth Potential Analysis
      10.10.1. By Country
      10.10.2. By Product Type
      10.10.3. By Application
      10.10.4. By Sales Channel
   10.11. Latin America HEPES Demand Share Forecast, 2019-2029

11. Europe HEPES Market Analysis and Forecast
   11.1. Introduction
      11.1.1. Basis Point Share (BPS) Analysis by Country
      11.1.2. Y-o-Y Growth Projections by Country
      11.1.3. Europe Average Pricing Analysis
   11.2. Europe HEPES Market Size and Volume Forecast by Country
      11.2.1. Germany
      11.2.2. France
      11.2.3. Italy
      11.2.4. U.K.
      11.2.5. Spain
      11.2.6. Russia
      11.2.7. Rest of Europe
   11.3. Absolute $ Opportunity Assessment by Country
   11.4. Europe HEPES Market Size and Volume Forecast by Application
      11.4.1. Cell Culture
      11.4.2. Protein Extraction
      11.4.3. Others
   11.5. Basis Point Share (BPS) Analysis by Application
   11.6. Y-o-Y Growth Projections by Application
   11.7. Europe HEPES Market Size and Volume Forecast by Type
      11.7.1. Crystalline Powder
      11.7.2. Buffering Agent
   11.8. Basis Point Share (BPS) Analysis by Type
   11.9. Y-o-Y Growth Projections by Type
   11.10. Market Attractiveness/Growth Potential Analysis
      11.10.1. By Country
      11.10.2. By Product Type
      11.10.3. By Aplication
      11.10.4. By Sales Channel
   11.11. Europe HEPES Demand Share, 2019-2029

12. Asia Pacific HEPES Market Analysis and Forecast
   12.1. Introduction
      12.1.1. Basis Point Share (BPS) Analysis by Country
      12.1.2. Y-o-Y Growth Projections by Country
      12.1.3. Asia Pacific Average Pricing Analysis
   12.2. Asia Pacific HEPES Market Size and Volume Forecast by Country
      12.2.1. China
      12.2.2. Japan
      12.2.3. South Korea
      12.2.4. India
      12.2.5. Australia
      12.2.6. Rest of Asia Pacific (APAC)
   12.3. Absolute $ Opportunity Assessment by Country
   12.4. Asia Pacific HEPES Market Size and Volume Forecast by Application
      12.4.1. Cell Culture
      12.4.2. Protein Extraction
      12.4.3. Others
   12.5. Basis Point Share (BPS) Analysis by Application
   12.6. Y-o-Y Growth Projections by Application
   12.7. Asia Pacific HEPES Market Size and Volume Forecast by Type
      12.7.1. Crystalline Powder
      12.7.2. Buffering Agent
   12.8. Basis Point Share (BPS) Analysis by Type
   12.9. Y-o-Y Growth Projections by Type
   12.10. Market Attractiveness/Growth Potential Analysis
      12.10.1. By Country
      12.10.2. By Product Type
      12.10.3. By Application
      12.10.4. By Sales Channel
   12.11. Asia Pacific HEPES Demand Share, 2019-2029

13. Middle East & Africa HEPES Market Analysis and Forecast
   13.1. Introduction
      13.1.1. Basis Point Share (BPS) Analysis by Country
      13.1.2. Y-o-Y Growth Projections by Country
      13.1.3. Asia Pacific Average Pricing Analysis
   13.2. Middle East & Africa HEPES Market Size and Volume Forecast by Country
      13.2.1. Saudi Arabia
      13.2.2. South Africa
      13.2.3. UAE
      13.2.4. Rest of Middle East & Africa (MEA)
   13.3. Absolute $ Opportunity Assessment by Country
   13.4. Middle East & Africa HEPES Market Size and Volume Forecast by Application
      13.4.1. Cell Culture
      13.4.2. Protein Extraction
      13.4.3. Others
   13.5. Basis Point Share (BPS) Analysis by Application
   13.6. Y-o-Y Growth Projections by Application
   13.7. Middle East & Africa HEPES Market Size and Volume Forecast by Type
      13.7.1. Crystalline Powder
      13.7.2. Buffering Agent
   13.8. Basis Point Share (BPS) Analysis by Type
   13.9. Y-o-Y Growth Projections by Type
   13.10. Market Attractiveness/Growth Potential Analysis
      13.10.1. By Country
      13.10.2. By Product Type
      13.10.3. By Application
      13.10.4. By Sales Channel
   13.11. Middle East & Africa HEPES Demand Share, 2019-2029

14. Competition Landscape
   14.1. Global HEPES Market: Market Share Analysis
   14.2. HEPES Distributors and Customers
   14.3. HEPES Market: Competitive Dashboard
   14.4. Company Profiles (Details – Overview, Financials, Developments, Strategy) 
      14.4.1. Merck KGaA Overview Financials Developments Strategic Outlook
      14.4.2. Formedium Overview Financials Developments Strategic Outlook
      14.4.3. Amresco Overview Financials Developments Strategic Outlook
      14.4.4. Thermo Fisher Scientific Overview Financials Developments Strategic Outlook
      14.4.5. Caisson Overview Financials Developments Strategic Outlook
      14.4.6. Lonza Overview Financials Developments Strategic Outlook
      14.4.7. Ge Healthcare Overview Financials Developments Strategic Outlook
      14.4.8. Biological Industries Overview Financials Developments Strategic Outlook
      14.4.9. Cayman Chemical Overview Financials Developments Strategic Outlook
      14.4.10. SERVA Electrophoresis GmbH Overview Financials Developments Strategic Outlook
      14.4.11. Tocris Bioscience Overview Financials Developments Strategic Outlook
      14.4.12. BioSpectra Overview Financials Developments Strategic Outlook
      14.4.13. Avantor Overview Financials Developments Strategic Outlook
      14.4.14. VWR International Overview Financials Developments Strategic Outlook
      14.4.15. Corning Overview Financials Developments Strategic Outlook
      14.4.16. Irvine Overview Financials Developments Strategic Outlook
      14.4.17. COMPANY 17 Overview Financials Developments Strategic Outlook
      14.4.18. COMPANY 18 Overview Financials Developments Strategic Outlook
      14.4.19. COMPANY 19 Overview Financials Developments Strategic Outlook
      14.4.20. COMPANY 20 Overview Financials Developments Strategic Outlook

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