Latest Update: Impact of current COVID-19 situation has been considered in this report while making the analysis.
Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market by Type (BC-001, CASI-2ME2, CRLX-101, Others), By Application (Solid Tumor, Acute Myelocytic Leukemia, Colorectal Cancer, Others) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030-report

Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market by Type (BC-001, CASI-2ME2, CRLX-101, Others), By Application (Solid Tumor, Acute Myelocytic Leukemia, Colorectal Cancer, Others) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030

Report ID: 195862 3300 Pharma & Healthcare 377 230 Pages 4.6 (34)
                                          

Market Overview:


The global hypoxia inducible factor 1 alpha inhibitor market is expected to grow at a CAGR of XX% during the forecast period from 2018 to 2030. The market growth can be attributed to the increasing incidence of cancer, rising awareness about cancer treatment options, and technological advancements in the field of oncology. The global hypoxia inducible factor 1 alpha inhibitor market is segmented by type into BC-001, CASI-2ME2, CRLX-101, and others. By application, the market is segmented into solid tumor, acute myelocytic leukemia (AML), colorectal cancer (CRC), and others. By region, the market is segmented into North America, Latin America Europe Asia Pacific and Middle East & Africa.


Global Hypoxia Inducible Factor 1 Alpha Inhibitor Industry Outlook


Product Definition:


Hypoxia Inducible Factor 1 Alpha Inhibitor is a protein that inhibits the function of Hypoxia Inducible Factor 1 Alpha (HIF-1α). HIF-1α is responsible for the transcription of genes involved in oxygen metabolism and angiogenesis. By inhibiting HIF-1α, Hypoxia Inducible Factor 1 Alpha Inhibitor reduces the ability of cells to adapt to hypoxic conditions. This makes it useful as a cancer therapy, as cancer cells often rely on hypoxic conditions to survive.


BC-001:


Hypoxia Inducible Factor 1 Alpha (HIF-1) is a protein that regulates the expression of genes involved in cellular respiration under hypoxic conditions. HIF-1 acts as an inhibitor and prevents the release of other inhibitors from mRNAs. The binding of BC-001 to the site blocks this inhibition, resulting in increased levels of mRNAs coding for cytoprotective proteins such as Bcl2, Bcl6, and Badh3.


CASI-2ME2:


CASI-2ME2 is a selective inhibitor of HIF1A. It has been reported to have more potency than the reference drug, Proteus mirabilis polysaccharide (PMP) in inhibiting hypoxia-inducible factor 1 alpha (HIF1A). CASI-2ME2 has also been found to be effective in vitro and in vivo against other human lung cancer cell lines besides NSCLC.


Application Insights:


Solid tumor accounted for the largest share in 2016 owing to the availability of effective treatment options such as chemotherapy and hypoxic therapy. Increasing prevalence of cancer worldwide is expected to be a major factor driving this segment during the forecast period. According to WHO, it has been estimated that globally 1 in 6 women and 1 in 5 men are estimated to develop cancer during their life span. Thus, increasing incidence rates coupled with rising awareness about early diagnosis is anticipated fuel market growth over the forecast period.


Regional Analysis:


North America was the largest revenue generating region in 2017. The growth is attributed to the presence of a substantial number of global players, high adoption rate for novel therapeutics and increasing government funding for cancer research. In addition, favorable reimbursement policies are also expected to drive market growth over the forecast period. Asia Pacific is estimated to be fastest growing region during the forecast period due to rising awareness about HIF1A INHIBITORS and availability of effective treatment methods against this condition in emerging countries such as China & India & South Korea etc. Moreover, increasing healthcare expenditure by governments and rise in disposable income will boost regional market development further on account of rapid economic development coupled with improving living standards among middle class population groups leading towards urbanization across these regions will have a positive impact on overall demand over next seven years as well (Figure 1).


Growth Factors:


  • Increasing prevalence of cancer: The increasing prevalence of cancer is one of the key growth drivers for the hypoxia inducible factor 1 alpha inhibitor market. According to a study by the American Cancer Society, it is estimated that around 1,685,210 new cases of cancer will be diagnosed in the U.S. in 2017 and around 600,920 people will die from this disease. This growing incidence rate of cancer is expected to drive demand for hypoxia inducible factor 1 alpha inhibitors over the forecast period.
  • Rising awareness about HIF-1 inhibitors: There is a rising awareness among physicians and patients about HIF-1 inhibitors and their potential benefits over traditional chemotherapy drugs used for treating various cancers such as renal cell carcinoma (RCC), non-small cell lung carcinoma (NSCLC), and glioblastoma multiforme (GBM). This growing awareness is expected to boost demand for these drugs over the forecast period.
  • Technological advancements: The development of novel technologies such as next generation sequencing (NGS) has led to identification of new targets involved in tumorigenesis which can be inhibited by HIF-1alpha inhibitors thereby providing an impetus to this market’s growth prospects . For instance, In February 2017, AstraZeneca announced that its investigational drug selumetinib was granted Breakthrough Therapy Designation by FDA for treatment naïve patients with advanced NRAS mutated

Scope Of The Report

Report Attributes

Report Details

Report Title

Hypoxia Inducible Factor 1 Alpha Inhibitor Market Research Report

By Type

BC-001, CASI-2ME2, CRLX-101, Others

By Application

Solid Tumor, Acute Myelocytic Leukemia, Colorectal Cancer, Others

By Companies

Aileron Therapeutics, Inc., CASI Pharmaceuticals Inc., Cerulean Pharma, Inc., F. Hoffmann-La Roche Ltd., InterMed Discovery GmbH, OncoImmune, Inc., Peloton Therapeutics, Inc., RXi Pharmaceuticals Corporation, Sorrento Therapeutics, Inc., Transcriptogen Ltd, Vascular Biogenics Ltd.

Regions Covered

North America, Europe, APAC, Latin America, MEA

Base Year

2021

Historical Year

2019 to 2020 (Data from 2010 can be provided as per availability)

Forecast Year

2030

Number of Pages

230

Number of Tables & Figures

161

Customization Available

Yes, the report can be customized as per your need.


Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Report Segments:

The global Hypoxia Inducible Factor 1 Alpha Inhibitor market is segmented on the basis of:

Types

BC-001, CASI-2ME2, CRLX-101, Others

The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.

Applications

Solid Tumor, Acute Myelocytic Leukemia, Colorectal Cancer, Others

The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.

Some of the companies that are profiled in this report are:

  1. Aileron Therapeutics, Inc.
  2. CASI Pharmaceuticals Inc.
  3. Cerulean Pharma, Inc.
  4. F. Hoffmann-La Roche Ltd.
  5. InterMed Discovery GmbH
  6. OncoImmune, Inc.
  7. Peloton Therapeutics, Inc.
  8. RXi Pharmaceuticals Corporation
  9. Sorrento Therapeutics, Inc.
  10. Transcriptogen Ltd
  11. Vascular Biogenics Ltd.

Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Overview


Highlights of The Hypoxia Inducible Factor 1 Alpha Inhibitor Market Report:

  1. The market structure and projections for the coming years.
  2. Drivers, restraints, opportunities, and current trends of market.
  3. Historical data and forecast.
  4. Estimations for the forecast period 2030.
  5. Developments and trends in the market.
  6. By Type:

    1. BC-001
    2. CASI-2ME2
    3. CRLX-101
    4. Others
  1. By Application:

    1. Solid Tumor
    2. Acute Myelocytic Leukemia
    3. Colorectal Cancer
    4. Others
  1. Market scenario by region, sub-region, and country.
  2. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
  3. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
  4. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Hypoxia Inducible Factor 1 Alpha Inhibitor Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.

Regional Analysis

  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.

The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.

How you may use our products:

  • Correctly Positioning New Products
  • Market Entry Strategies
  • Business Expansion Strategies
  • Consumer Insights
  • Understanding Competition Scenario
  • Product & Brand Management
  • Channel & Customer Management
  • Identifying Appropriate Advertising Appeals

Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Statistics

8 Reasons to Buy This Report

  1. Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
  2. Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
  3. Implemented Robust Methodology to Prepare the Report
  4. Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
  5. Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
  6. Provides Information About the Top-winning Strategies Implemented by Industry Players.
  7. In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
  8. Customization of the Report Available

Frequently Asked Questions?


Hypoxia Inducible Factor 1 Alpha Inhibitor (HIF1A inhibitor) is a type of medication that helps to block the action of HIF1A, which is responsible for inducing hypoxia in cells. This can help to prevent or reduce the severity and duration of hypoxic conditions such as altitude sickness.

Some of the major players in the hypoxia inducible factor 1 alpha inhibitor market are Aileron Therapeutics, Inc., CASI Pharmaceuticals Inc., Cerulean Pharma, Inc., F. Hoffmann-La Roche Ltd., InterMed Discovery GmbH, OncoImmune, Inc., Peloton Therapeutics, Inc., RXi Pharmaceuticals Corporation, Sorrento Therapeutics, Inc., Transcriptogen Ltd, Vascular Biogenics Ltd..

                                            
1. Executive Summary

2. Assumptions and Acronyms Used

3. Research Methodology

4. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Overview
   4.1. Introduction
      4.1.1. Market Taxonomy
      4.1.2. Market Definition
   4.2. Macro-Economic Factors
      4.2.1. Industry Outlook
   4.3. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Dynamics
      4.3.1. Market Drivers
      4.3.2. Market Restraints
      4.3.3. Opportunity
      4.3.4. Market Trends
   4.4. Hypoxia Inducible Factor 1 Alpha Inhibitor Market - Supply Chain
   4.5. Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Forecast
      4.5.1. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size (US$ Mn) and Y-o-Y Growth
      4.5.2. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size (000’ Units) and Y-o-Y Growth
      4.5.3. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Absolute $ Opportunity

5. Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast by Type
   5.1. Market Trends
   5.2. Introduction
      5.2.1. Basis Point Share (BPS) Analysis by Type
      5.2.2. Y-o-Y Growth Projections by Type
   5.3. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Type
      5.3.1. BC-001
      5.3.2. CASI-2ME2
      5.3.3. CRLX-101
      5.3.4. Others
   5.4. Absolute $ Opportunity Assessment by Type
   5.5. Market Attractiveness/Growth Potential Analysis by Type

6. Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast by Application
   6.1. Market Trends
   6.2. Introduction
      6.2.1. Basis Point Share (BPS) Analysis by Application
      6.2.2. Y-o-Y Growth Projections by Application
   6.3. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Application
      6.3.1. Solid Tumor
      6.3.2. Acute Myelocytic Leukemia
      6.3.3. Colorectal Cancer
      6.3.4. Others
   6.4. Absolute $ Opportunity Assessment by Application
   6.5. Market Attractiveness/Growth Potential Analysis by Application

7. Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast by Sales Channel
   7.1. Market Trends
   7.2. Introduction
      7.2.1. Basis Point Share (BPS) Analysis by Sales Channel 
      7.2.2. Y-o-Y Growth Projections by Sales Channel
   7.3. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Sales Channel 
      7.3.1. Manufacturer/Distributor/Service Provider
      7.3.2. Aftermarket
   7.4. Absolute $ Opportunity Assessment by Sales Channel
   7.5. Market Attractiveness/Growth Potential Analysis by Sales Channel

8. Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast by Region
   8.1. Market Trends
   8.2. Introduction
      8.2.1. Basis Point Share (BPS) Analysis by Region
      8.2.2. Y-o-Y Growth Projections by Region
   8.3. Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Region
      8.3.1. North America
      8.3.2. Latin America
      8.3.3. Europe
      8.3.4. Asia Pacific
      8.3.5. Middle East and Africa (MEA)
   8.4. Absolute $ Opportunity Assessment by Region
   8.5. Market Attractiveness/Growth Potential Analysis by Region
   8.6. Global Hypoxia Inducible Factor 1 Alpha Inhibitor Demand Share Forecast, 2019-2026

9. North America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast
   9.1. Introduction
      9.1.1. Basis Point Share (BPS) Analysis by Country
      9.1.2. Y-o-Y Growth Projections by Country
   9.2. North America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Country
      9.2.1. U.S.
      9.2.2. Canada
   9.3. Absolute $ Opportunity Assessment by Country
   9.4. North America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Application
      9.4.1. Solid Tumor
      9.4.2. Acute Myelocytic Leukemia
      9.4.3. Colorectal Cancer
      9.4.4. Others
   9.5. Basis Point Share (BPS) Analysis by Application
   9.6. Y-o-Y Growth Projections by Application
   9.7. North America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Type
      9.7.1. BC-001
      9.7.2. CASI-2ME2
      9.7.3. CRLX-101
      9.7.4. Others
   9.8. Basis Point Share (BPS) Analysis by Type
   9.9. Y-o-Y Growth Projections by Type
   9.10. Market Attractiveness/Growth Potential Analysis
      9.10.1. By Country
      9.10.2. By Product Type
      9.10.3. By Application
      9.10.4. By Sales Channel
   9.11. North America Hypoxia Inducible Factor 1 Alpha Inhibitor Demand Share Forecast, 2019-2026

10. Latin America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast
   10.1. Introduction
      10.1.1. Basis Point Share (BPS) Analysis by Country
      10.1.2. Y-o-Y Growth Projections by Country
      10.1.3. Latin America Average Pricing Analysis
   10.2. Latin America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Country
      10.2.1. Brazil
      10.2.2. Mexico
      10.2.3. Rest of Latin America
   10.3. Absolute $ Opportunity Assessment by Country
   10.4. Latin America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Application
      10.4.1. Solid Tumor
      10.4.2. Acute Myelocytic Leukemia
      10.4.3. Colorectal Cancer
      10.4.4. Others
   10.5. Basis Point Share (BPS) Analysis by Application
   10.6. Y-o-Y Growth Projections by Application
   10.7. Latin America Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Type
      10.7.1. BC-001
      10.7.2. CASI-2ME2
      10.7.3. CRLX-101
      10.7.4. Others
   10.8. Basis Point Share (BPS) Analysis by Type
   10.9. Y-o-Y Growth Projections by Type
   10.10. Market Attractiveness/Growth Potential Analysis
      10.10.1. By Country
      10.10.2. By Product Type
      10.10.3. By Application
      10.10.4. By Sales Channel
   10.11. Latin America Hypoxia Inducible Factor 1 Alpha Inhibitor Demand Share Forecast, 2019-2026

11. Europe Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast
   11.1. Introduction
      11.1.1. Basis Point Share (BPS) Analysis by Country
      11.1.2. Y-o-Y Growth Projections by Country
      11.1.3. Europe Average Pricing Analysis
   11.2. Europe Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Country
      11.2.1. Germany
      11.2.2. France
      11.2.3. Italy
      11.2.4. U.K.
      11.2.5. Spain
      11.2.6. Russia
      11.2.7. Rest of Europe
   11.3. Absolute $ Opportunity Assessment by Country
   11.4. Europe Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Application
      11.4.1. Solid Tumor
      11.4.2. Acute Myelocytic Leukemia
      11.4.3. Colorectal Cancer
      11.4.4. Others
   11.5. Basis Point Share (BPS) Analysis by Application
   11.6. Y-o-Y Growth Projections by Application
   11.7. Europe Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Type
      11.7.1. C-001
      11.7.2. CASI-2ME2
      11.7.3. CRLX-101
      11.7.4. Others
   11.8. Basis Point Share (BPS) Analysis by Type
   11.9. Y-o-Y Growth Projections by Type
   11.10. Market Attractiveness/Growth Potential Analysis
      11.10.1. By Country
      11.10.2. By Product Type
      11.10.3. By Application
      11.10.4. By Sales Channel
   11.11. Europe Hypoxia Inducible Factor 1 Alpha Inhibitor Demand Share, 2019-2026

12. Asia Pacific Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast
   12.1. Introduction
      12.1.1. Basis Point Share (BPS) Analysis by Country
      12.1.2. Y-o-Y Growth Projections by Country
      12.1.3. Asia Pacific Average Pricing Analysis
   12.2. Asia Pacific Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Country
      12.2.1. China
      12.2.2. Japan
      12.2.3. South Korea
      12.2.4. India
      12.2.5. Australia
      12.2.6. Rest of Asia Pacific (APAC)
   12.3. Absolute $ Opportunity Assessment by Country
   12.4. Asia Pacific Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Application
      12.4.1. Solid Tumor
      12.4.2. Acute Myelocytic Leukemia
      12.4.3. Colorectal Cancer
      12.4.4. Others
   12.5. Basis Point Share (BPS) Analysis by Application
   12.6. Y-o-Y Growth Projections by Application
   12.7. Asia Pacific Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Type
      12.7.1. BC-001
      12.7.2. CASI-2ME2
      12.7.3. CRLX-101
      12.7.4. Others
   12.8. Basis Point Share (BPS) Analysis by Type
   12.9. Y-o-Y Growth Projections by Type
   12.10. Market Attractiveness/Growth Potential Analysis
      12.10.1. By Country
      12.10.2. By Product Type
      12.10.3. By Application
      12.10.4. By Sales Channel
   12.11. Asia Pacific Hypoxia Inducible Factor 1 Alpha Inhibitor Demand Share, 2019-2026

13. Middle East & Africa Hypoxia Inducible Factor 1 Alpha Inhibitor Market Analysis and Forecast
   13.1. Introduction
      13.1.1. Basis Point Share (BPS) Analysis by Country
      13.1.2. Y-o-Y Growth Projections by Country
      13.1.3. Asia Pacific Average Pricing Analysis
   13.2. Middle East & Africa Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Country
      13.2.1. Saudi Arabia
      13.2.2. South Africa
      13.2.3. UAE
      13.2.4. Rest of Middle East & Africa (MEA)
   13.3. Absolute $ Opportunity Assessment by Country
   13.4. Middle East & Africa Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Application
      13.4.1. Solid Tumor
      13.4.2. Acute Myelocytic Leukemia
      13.4.3. Colorectal Cancer
      13.4.4. Others
   13.5. Basis Point Share (BPS) Analysis by Application
   13.6. Y-o-Y Growth Projections by Application
   13.7. Middle East & Africa Hypoxia Inducible Factor 1 Alpha Inhibitor Market Size and Volume Forecast by Type
      13.7.1. BC-001
      13.7.2. CASI-2ME2
      13.7.3. CRLX-101
      13.7.4. Others
   13.8. Basis Point Share (BPS) Analysis by Type
   13.9. Y-o-Y Growth Projections by Type
   13.10. Market Attractiveness/Growth Potential Analysis
      13.10.1. By Country
      13.10.2. By Product Type
      13.10.3. By Application
      13.10.4. By Sales Channel
   13.11. Middle East & Africa Hypoxia Inducible Factor 1 Alpha Inhibitor Demand Share, 2019-2026

14. Competition Landscape
   14.1. Global Hypoxia Inducible Factor 1 Alpha Inhibitor Market: Market Share Analysis
   14.2. Hypoxia Inducible Factor 1 Alpha Inhibitor Distributors and Customers
   14.3. Hypoxia Inducible Factor 1 Alpha Inhibitor Market: Competitive Dashboard
   14.4. Company Profiles (Details – Overview, Financials, Developments, Strategy) 
      14.4.1. Aileron Therapeutics, Inc.
         14.4.1.1. Overview
         14.4.1.2. Financials
         14.4.1.3. Developments
         14.4.1.4. Strategic Outlook
      14.4.2. CASI Pharmaceuticals Inc.
         14.4.2.1. Overview
         14.4.2.2. Financials
         14.4.2.3. Developments
         14.4.2.4. Strategic Outlook
      14.4.3. Cerulean Pharma, Inc.
         14.4.3.1. Overview
         14.4.3.2. Financials
         14.4.3.3. Developments
         14.4.3.4. Strategic Outlook
      14.4.4. F. Hoffmann-La Roche Ltd.
         14.4.4.1. Overview
         14.4.4.2. Financials
         14.4.4.3. Developments
         14.4.4.4. Strategic Outlook
      14.4.5. InterMed Discovery GmbH
         14.4.5.1. Overview
         14.4.5.2. Financials
         14.4.5.3. Developments
         14.4.5.4. Strategic Outlook
      14.4.6. OncoImmune, Inc.
         14.4.6.1. Overview
         14.4.6.2. Financials
         14.4.6.3. Developments
         14.4.6.4. Strategic Outlook
      14.4.7. Peloton Therapeutics, Inc.
         14.4.7.1. Overview
         14.4.7.2. Financials
         14.4.7.3. Developments
         14.4.7.4. Strategic Outlook
      14.4.8. RXi Pharmaceuticals Corporation
         14.4.8.1. Overview
         14.4.8.2. Financials
         14.4.8.3. Developments
         14.4.8.4. Strategic Outlook
      14.4.9. Sorrento Therapeutics, Inc.
         14.4.9.1. Overview
         14.4.9.2. Financials
         14.4.9.3. Developments
         14.4.9.4. Strategic Outlook
      14.4.10. Transcriptogen Ltd
         14.4.10.1. Overview
         14.4.10.2. Financials
         14.4.10.3. Developments
         14.4.10.4. Strategic Outlook
      14.4.11. Vascular Biogenics Ltd.
         14.4.11.1. Overview
         14.4.11.2. Financials
         14.4.11.3. Developments
         14.4.11.4. Strategic Outlook
      14.4.12. COMPANY 12
         14.4.12.1. Overview
         14.4.12.2. Financials
         14.4.12.3. Developments
         14.4.12.4. Strategic Outlook
      14.4.13. COMPANY 13
         14.4.13.1. Overview
         14.4.13.2. Financials
         14.4.13.3. Developments
         14.4.13.4. Strategic Outlook
      14.4.14. COMPANY 14
         14.4.14.1. Overview
         14.4.14.2. Financials
         14.4.14.3. Developments
         14.4.14.4. Strategic Outlook
      14.4.15. COMPANY 15
         14.4.15.1. Overview
         14.4.15.2. Financials
         14.4.15.3. Developments
         14.4.15.4. Strategic Outlook
      14.4.16. COMPANY 16
         14.4.16.1. Overview
         14.4.16.2. Financials
         14.4.16.3. Developments
         14.4.16.4. Strategic Outlook
      14.4.17. COMPANY 17
         14.4.17.1. Overview
         14.4.17.2. Financials
         14.4.17.3. Developments
         14.4.17.4. Strategic Outlook
      14.4.18. COMPANY 18
         14.4.18.1. Overview
         14.4.18.2. Financials
         14.4.18.3. Developments
         14.4.18.4. Strategic Outlook
      14.4.19. COMPANY 19
         14.4.19.1. Overview
         14.4.19.2. Financials
         14.4.19.3. Developments
         14.4.19.4. Strategic Outlook
      14.4.20. COMPANY 20
         14.4.20.1. Overview
         14.4.20.2. Financials
         14.4.20.3. Developments
         14.4.20.4. Strategic Outlook

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