Latest Update: Impact of current COVID-19 situation has been considered in this report while making the analysis.
Global Methotrexate Drugs Market by Type (2.5mg/ml, 2mg/ml), By Application (Cancer, Autoimmune Diseases, Other) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030-report

Global Methotrexate Drugs Market by Type (2.5mg/ml, 2mg/ml), By Application (Cancer, Autoimmune Diseases, Other) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030

Report ID: 137806 3300 Pharma & Healthcare 377 244 Pages 5 (33)

Market Overview:

The global methotrexate drugs market is expected to grow at a CAGR of 5.5% during the forecast period from 2018 to 2030. The growth in this market can be attributed to the increasing prevalence of cancer and autoimmune diseases, and the rising demand for effective treatment options. By type, the global methotrexate drugs market is segmented into 2.5mg/ml and 2mg/ml segments. The 2mg/ml segment is expected to account for a larger share of the global market than the 2.5mg/ml segment during the forecast period owing to its higher efficacy in treating various diseases such as cancer and autoimmune diseases. By application, the global methotrexate drugs market is divided into cancer, autoimmune diseases, and other applications segments.

Global Methotrexate Drugs Industry Outlook

Product Definition:

Methotrexate is a drug used to treat cancer, arthritis, and other diseases. It is important because it can help to prevent the growth of cancer cells, reduce inflammation, and improve joint function in people with arthritis.


Methotrexate is a drug that is used to treat cancer and arthritis. It works by damaging the cells that are responsible for causing pain. The most common side effects of methotrexate include skin rash, itching, hair loss, mouth sores, bone marrow suppression (reduced production of blood cells), liver damage and gastrointestinal disturbance among others.

The global methotrexate drugs market was valued at USD 1.8 billion in 2015.


2mg/ml is the concentration of methotrexate in oral solution and it's used as an anti-cancer drug. It works by causing cancer cell death. The oral solution contains 2 mg of methotrexate per ml, which is equivalent to 6 minims of actual medication.

Methotrexate (MTX) is a chemotherapy drug that interferes with the growth of cancer cells and stops them from reproducing.

Application Insights:

Cancer was the dominant application segment and accounted for over 75% of total market volume in 2017. The growing use of methotrexate in cancer treatment, particularly breast cancer, is one of the key factors driving this segment. Breast cancer is a major concern for many women as it accounts for around 40% to 50% cases globally. According to, around 5-10% of women develop invasive breast carcinoma every year which leads to death approximately 1-2%.

The rising prevalence coupled with availability of advanced drugs such as Kadcyla (Doxil) and Zomacton (Somatropin) are expected to drive demand from the cancer segment over the forecast period. Other applications include rheumatoid arthritis and psoriasis among others; however these conditions are not prominent enough to create separate segments on their own so they will be included under other applications category during forecasting period.

Regional Analysis:

North America dominated the global market in 2017, with a revenue share of over 39.0%. The presence of key players and well-established healthcare infrastructure are some factors accounting for its largest share. Furthermore, increasing R&D activities to develop new formulations and improve existing therapies is expected to drive the region’s growth during the forecast period.

Asia Pacific is anticipated to witness lucrative growth over the forecast period owing to rising disposable income levels, improving economic conditions, expanding middle-class population base along with growing awareness about early diagnosis in emerging countries such as China and India. These factors are expected to contribute toward increased demand for methotrexate drugs in this region during the forecast period. Moreover, favorable government initiatives pertaining towards improved access & coverage are also likely boost regional product demand during 2018 - 2030  time frame.

Growth Factors:

  • Increasing incidence of cancer: The global incidence of cancer is increasing at an alarming rate. This is expected to drive the demand for methotrexate drugs in the coming years.
  • Rising awareness about methotrexate drugs: There is a growing awareness among people about the benefits of using methotrexate drugs for various medical conditions. This is likely to boost the demand for these drugs in the coming years.
  • Growing use of methotrexate drugs in combination therapy: Methotrexate drugs are increasingly being used in combination with other therapies to achieve better results. This is likely to fuel the growth of this market in the near future.

Scope Of The Report

Report Attributes

Report Details

Report Title

Methotrexate Drugs Market Research Report

By Type

2.5mg/ml, 2mg/ml

By Application

Cancer, Autoimmune Diseases, Other

By Companies

Silvergate Pharmaceuticals, ...

Regions Covered

North America, Europe, APAC, Latin America, MEA

Base Year


Historical Year

2019 to 2020 (Data from 2010 can be provided as per availability)

Forecast Year


Number of Pages


Number of Tables & Figures


Customization Available

Yes, the report can be customized as per your need.

Global Methotrexate Drugs Market Report Segments:

The global Methotrexate Drugs market is segmented on the basis of:


2.5mg/ml, 2mg/ml

The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.


Cancer, Autoimmune Diseases, Other

The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.

Some of the companies that are profiled in this report are:

  1. Silvergate Pharmaceuticals
  2. ...

Global Methotrexate Drugs Market Overview

Highlights of The Methotrexate Drugs Market Report:

  1. The market structure and projections for the coming years.
  2. Drivers, restraints, opportunities, and current trends of market.
  3. Historical data and forecast.
  4. Estimations for the forecast period 2030.
  5. Developments and trends in the market.
  6. By Type:

    1. 2.5mg/ml
    2. 2mg/ml
  1. By Application:

    1. Cancer
    2. Autoimmune Diseases
    3. Other
  1. Market scenario by region, sub-region, and country.
  2. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
  3. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
  4. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Methotrexate Drugs Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.

Regional Analysis

  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.

The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.

How you may use our products:

  • Correctly Positioning New Products
  • Market Entry Strategies
  • Business Expansion Strategies
  • Consumer Insights
  • Understanding Competition Scenario
  • Product & Brand Management
  • Channel & Customer Management
  • Identifying Appropriate Advertising Appeals

Global Methotrexate Drugs Market Statistics

8 Reasons to Buy This Report

  1. Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
  2. Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
  3. Implemented Robust Methodology to Prepare the Report
  4. Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
  5. Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
  6. Provides Information About the Top-winning Strategies Implemented by Industry Players.
  7. In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
  8. Customization of the Report Available

Frequently Asked Questions?

Methotrexate drugs are used to treat cancer. Methotrexate works by stopping the growth of cancer cells.

Some of the major companies in the methotrexate drugs market are Silvergate Pharmaceuticals.

The methotrexate drugs market is expected to grow at a compound annual growth rate of 5.5%.

1. Executive Summary

2. Assumptions and Acronyms Used

3. Research Methodology

4. Methotrexate Drugs Market Overview
   4.1. Introduction
      4.1.1. Market Taxonomy
      4.1.2. Market Definition
   4.2. Macro-Economic Factors
      4.2.1. Industry Outlook
   4.3. Methotrexate Drugs Market Dynamics
      4.3.1. Market Drivers
      4.3.2. Market Restraints
      4.3.3. Opportunity
      4.3.4. Market Trends
   4.4. Methotrexate Drugs Market - Supply Chain
   4.5. Global Methotrexate Drugs Market Forecast
      4.5.1. Methotrexate Drugs Market Size (US$ Mn) and Y-o-Y Growth
      4.5.2. Methotrexate Drugs Market Size (000’ Units) and Y-o-Y Growth
      4.5.3. Methotrexate Drugs Market Absolute $ Opportunity

5. Global Methotrexate Drugs Market Analysis and Forecast by Type
   5.1. Market Trends
   5.2. Introduction
      5.2.1. Basis Point Share (BPS) Analysis by Type
      5.2.2. Y-o-Y Growth Projections by Type
   5.3. Methotrexate Drugs Market Size and Volume Forecast by Type
      5.3.1. 2.5mg/ml
      5.3.2. 2mg/ml
   5.4. Absolute $ Opportunity Assessment by Type
   5.5. Market Attractiveness/Growth Potential Analysis by Type

6. Global Methotrexate Drugs Market Analysis and Forecast by Application
   6.1. Market Trends
   6.2. Introduction
      6.2.1. Basis Point Share (BPS) Analysis by Application
      6.2.2. Y-o-Y Growth Projections by Application
   6.3. Methotrexate Drugs Market Size and Volume Forecast by Application
      6.3.1. Cancer
      6.3.2. Autoimmune Diseases
      6.3.3. Other
   6.4. Absolute $ Opportunity Assessment by Application
   6.5. Market Attractiveness/Growth Potential Analysis by Application

7. Global Methotrexate Drugs Market Analysis and Forecast by Sales Channel
   7.1. Market Trends
   7.2. Introduction
      7.2.1. Basis Point Share (BPS) Analysis by Sales Channel 
      7.2.2. Y-o-Y Growth Projections by Sales Channel
   7.3. Methotrexate Drugs Market Size and Volume Forecast by Sales Channel 
      7.3.1. Manufacturer/Distributor/Service Provider
      7.3.2. Aftermarket
   7.4. Absolute $ Opportunity Assessment by Sales Channel
   7.5. Market Attractiveness/Growth Potential Analysis by Sales Channel

8. Global Methotrexate Drugs Market Analysis and Forecast by Region
   8.1. Market Trends
   8.2. Introduction
      8.2.1. Basis Point Share (BPS) Analysis by Region
      8.2.2. Y-o-Y Growth Projections by Region
   8.3. Methotrexate Drugs Market Size and Volume Forecast by Region
      8.3.1. North America
      8.3.2. Latin America
      8.3.3. Europe
      8.3.4. Asia Pacific
      8.3.5. Middle East and Africa (MEA)
   8.4. Absolute $ Opportunity Assessment by Region
   8.5. Market Attractiveness/Growth Potential Analysis by Region
   8.6. Global Methotrexate Drugs Demand Share Forecast, 2019-2029

9. North America Methotrexate Drugs Market Analysis and Forecast
   9.1. Introduction
      9.1.1. Basis Point Share (BPS) Analysis by Country
      9.1.2. Y-o-Y Growth Projections by Country
   9.2. North America Methotrexate Drugs Market Size and Volume Forecast by Country
      9.2.1. U.S.
      9.2.2. Canada
   9.3. Absolute $ Opportunity Assessment by Country
   9.4. North America Methotrexate Drugs Market Size and Volume Forecast by Application
      9.4.1. Cancer
      9.4.2. Autoimmune Diseases
      9.4.3. Other
   9.5. Basis Point Share (BPS) Analysis by Application
   9.6. Y-o-Y Growth Projections by Application
   9.7. North America Methotrexate Drugs Market Size and Volume Forecast by Type
      9.7.1. 2.5mg/ml
      9.7.2. 2mg/ml
   9.8. Basis Point Share (BPS) Analysis by Type
   9.9. Y-o-Y Growth Projections by Type
   9.10. Market Attractiveness/Growth Potential Analysis
      9.10.1. By Country
      9.10.2. By Product Type
      9.10.3. By Application
      9.10.4. By Sales Channel
   9.11. North America Methotrexate Drugs Demand Share Forecast, 2019-2029

10. Latin America Methotrexate Drugs Market Analysis and Forecast
   10.1. Introduction
      10.1.1. Basis Point Share (BPS) Analysis by Country
      10.1.2. Y-o-Y Growth Projections by Country
      10.1.3. Latin America Average Pricing Analysis
   10.2. Latin America Methotrexate Drugs Market Size and Volume Forecast by Country
      10.2.1. Brazil
      10.2.2. Mexico
      10.2.3. Rest of Latin America
   10.3. Absolute $ Opportunity Assessment by Country
   10.4. Latin America Methotrexate Drugs Market Size and Volume Forecast by Application
      10.4.1. Cancer
      10.4.2. Autoimmune Diseases
      10.4.3. Other
   10.5. Basis Point Share (BPS) Analysis by Application
   10.6. Y-o-Y Growth Projections by Application
   10.7. Latin America Methotrexate Drugs Market Size and Volume Forecast by Type
      10.7.1. 2.5mg/ml
      10.7.2. 2mg/ml
   10.8. Basis Point Share (BPS) Analysis by Type
   10.9. Y-o-Y Growth Projections by Type
   10.10. Market Attractiveness/Growth Potential Analysis
      10.10.1. By Country
      10.10.2. By Product Type
      10.10.3. By Application
      10.10.4. By Sales Channel
   10.11. Latin America Methotrexate Drugs Demand Share Forecast, 2019-2029

11. Europe Methotrexate Drugs Market Analysis and Forecast
   11.1. Introduction
      11.1.1. Basis Point Share (BPS) Analysis by Country
      11.1.2. Y-o-Y Growth Projections by Country
      11.1.3. Europe Average Pricing Analysis
   11.2. Europe Methotrexate Drugs Market Size and Volume Forecast by Country
      11.2.1. Germany
      11.2.2. France
      11.2.3. Italy
      11.2.4. U.K.
      11.2.5. Spain
      11.2.6. Russia
      11.2.7. Rest of Europe
   11.3. Absolute $ Opportunity Assessment by Country
   11.4. Europe Methotrexate Drugs Market Size and Volume Forecast by Application
      11.4.1. Cancer
      11.4.2. Autoimmune Diseases
      11.4.3. Other
   11.5. Basis Point Share (BPS) Analysis by Application
   11.6. Y-o-Y Growth Projections by Application
   11.7. Europe Methotrexate Drugs Market Size and Volume Forecast by Type
      11.7.1. 2.5mg/ml
      11.7.2. 2mg/ml
   11.8. Basis Point Share (BPS) Analysis by Type
   11.9. Y-o-Y Growth Projections by Type
   11.10. Market Attractiveness/Gowth Potential Analysis
      11.10.1. By Country
      11.10.2. By Product Type
      11.10.3. By Application
      11.10.4. By Sales Channel
   11.11. Europe Methotrexate Drugs Demand Share, 2019-2029

12. Asia Pacific Methotrexate Drugs Market Analysis and Forecast
   12.1. Introduction
      12.1.1. Basis Point Share (BPS) Analysis by Country
      12.1.2. Y-o-Y Growth Projections by Country
      12.1.3. Asia Pacific Average Pricing Analysis
   12.2. Asia Pacific Methotrexate Drugs Market Size and Volume Forecast by Country
      12.2.1. China
      12.2.2. Japan
      12.2.3. South Korea
      12.2.4. India
      12.2.5. Australia
      12.2.6. Rest of Asia Pacific (APAC)
   12.3. Absolute $ Opportunity Assessment by Country
   12.4. Asia Pacific Methotrexate Drugs Market Size and Volume Forecast by Application
      12.4.1. Cancer
      12.4.2. Autoimmune Diseases
      12.4.3. Other
   12.5. Basis Point Share (BPS) Analysis by Application
   12.6. Y-o-Y Growth Projections by Application
   12.7. Asia Pacific Methotrexate Drugs Market Size and Volume Forecast by Type
      12.7.1. 2.5mg/ml
      12.7.2. 2mg/ml
   12.8. Basis Point Share (BPS) Analysis by Type
   12.9. Y-o-Y Growth Projections by Type
   12.10. Market Attractiveness/Growth Potential Analysis
      12.10.1. By Country
      12.10.2. By Product Type
      12.10.3. By Application
      12.10.4. By Sales Channel
   12.11. Asia Pacific Methotrexate Drugs Demand Share, 2019-2029

13. Middle East & Africa Methotrexate Drugs Market Analysis and Forecast
   13.1. Introduction
      13.1.1. Basis Point Share (BPS) Analysis by Country
      13.1.2. Y-o-Y Growth Projections by Country
      13.1.3. Asia Pacific Average Pricing Analysis
   13.2. Middle East & Africa Methotrexate Drugs Market Size and Volume Forecast by Country
      13.2.1. Saudi Arabia
      13.2.2. South Africa
      13.2.3. UAE
      13.2.4. Rest of Middle East & Africa (MEA)
   13.3. Absolute $ Opportunity Assessment by Country
   13.4. Middle East & Africa Methotrexate Drugs Market Size and Volume Forecast by Application
      13.4.1. Cancer
      13.4.2. Autoimmune Diseases
      13.4.3. Other
   13.5. Basis Point Share (BPS) Analysis by Application
   13.6. Y-o-Y Growth Projections by Application
   13.7. Middle East & Africa Methotrexate Drugs Market Size and Volume Forecast by Type
      13.7.1. 2.5mg/ml
      13.7.2. 2mg/ml
   13.8. Basis Point Share (BPS) Analysis by Type
   13.9. Y-o-Y Growth Projections by Type
   13.10. Market Attractiveness/Growth Potential Analysis
      13.10.1. By Country
      13.10.2. By Product Type
      13.10.3. By Application
      13.10.4. By Sales Channel
   13.11. Middle East & Africa Methotrexate Drugs Demand Share, 2019-2029

14. Competition Landscape
   14.1. Global Methotrexate Drugs Market: Market Share Analysis
   14.2. Methotrexate Drugs Distributors and Customers
   14.3. Methotrexate Drugs Market: Competitive Dashboard
   14.4. Company Profiles (Details – Overview, Financials, Developments, Strategy) 
      14.4.1. Silvergate Pharmaceuticals Overview Financials Developments Strategic Outlook
      14.4.2. ... Overview Financials Developments Strategic Outlook
      14.4.3. COMPANY3 Overview Financials Developments Strategic Outlook
      14.4.4. COMPANY4 Overview Financials Developments Strategic Outlook
      14.4.5. COMPANY5 Overview Financials Developments Strategic Outlook
      14.4.6. COMPANY6 Overview Financials Developments Strategic Outlook
      14.4.7. COMPANY7 Overview Financials Developments Strategic Outlook
      14.4.8. COMPANY8 Overview Financials Developments Strategic Outlook
      14.4.9. COMPANY9 Overview Financials Developments Strategic Outlook
      14.4.10. COMPANY 10 Overview Financials Developments Strategic Outlook
      14.4.11. COMPANY 11 Overview Financials Developments Strategic Outlook
      14.4.12. COMPANY 12 Overview Financials Developments Strategic Outlook
      14.4.13. COMPANY 13 Overview Financials Developments Strategic Outlook
      14.4.14. COMPANY 14 Overview Financials Developments Strategic Outlook
      14.4.15. COMPANY 15 Overview Financials Developments Strategic Outlook
      14.4.16. COMPANY 16 Overview Financials Developments Strategic Outlook
      14.4.17. COMPANY 17 Overview Financials Developments Strategic Outlook
      14.4.18. COMPANY 18 Overview Financials Developments Strategic Outlook
      14.4.19. COMPANY 19 Overview Financials Developments Strategic Outlook
      14.4.20. COMPANY 20 Overview Financials Developments Strategic Outlook

Our Trusted Clients

Contact Us