Latest Update: Impact of current COVID-19 situation has been considered in this report while making the analysis.
Global Orthobiologics Market by Type (Bone Growth Stimulators (BGS), Viscosupplements, Bone Graft Substitute), By Application (Hospitals, Ambulatory Surgical Centres, Orthopaedics Clinics) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030-report

Global Orthobiologics Market by Type (Bone Growth Stimulators (BGS), Viscosupplements, Bone Graft Substitute), By Application (Hospitals, Ambulatory Surgical Centres, Orthopaedics Clinics) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030

Report ID: 170584 3300 Pharma & Healthcare 377 245 Pages 4.5 (38)
                                          

Market Overview:


The global orthobiologics market is expected to grow at a CAGR of 7.5% from 2018 to 2030. The growth in the market can be attributed to factors such as rising incidence of bone and joint disorders, increasing demand for minimally invasive surgeries, and technological advancements in orthobiologics products. Based on type, the global orthobiologics market is segmented into bone growth stimulators (BGS), viscosupplements, and bone graft substitutes. The BGS segment is expected to grow at the highest CAGR during the forecast period owing to its ability to promote natural healing process and improve functional outcomes after surgery. Based on application, the global orthobiologics market is segmented into hospitals, ambulatory surgical centres (ASCs), and orthopaedic clinics. The hospitals segment accounted for the largest share of the global Orthobiologics Market in 2017 due to rising number of hip replacement surgeries across regions.


Global Orthobiologics Industry Outlook


Product Definition:


Orthobiologics is the term used to describe the use of natural or synthetic materials to improve bone healing and regeneration. Orthobiologics can be used to treat a variety of orthopedic conditions, including fractures, joint injuries, and osteoarthritis. The use of orthobiologics may improve healing times and reduce the need for surgery.


Bone Growth Stimulators (BGS):


Bone Growth Stimulators (BGS) is a therapy device that uses electrical stimulation to promote bone growth. It’s main function is to stimulate the cells in order to accelerate the healing process of bones and joints. BGS are used for treating conditions such as osteoporosis, anemia, arthritis, and other degenerative diseases that cause weak bones.


The global orthobiologics market size was valued at USD 4.5 billion in 2016.


Viscosupplements:


Viscosupplements are viscoelastic agents that help in the restoration of joint fluidity and cartilage by inhibiting proteolytic enzymes. They are used as a nutritional supplement to improve joint function, reduce inflammation & pain and increase mobility in arthritic joints. Viscosupplements can be administered orally or topically depending upon the type of arthritis being treated.


Application Insights:


The market is segmented by application into hospitals, ambulatory surgical centers, and orthopedic clinics/hospitals. The hospital segment dominated the overall industry in terms of revenue in 2017 owing to factors such as increasing geriatric population and rising number of trauma cases. According to a study published by the WHO, it was estimated that globally one quarter of people aged 65 years or above were injured or disabled in 2015. This factor is expected to drive demand for OA therapies during the forecast period.


In addition, growing awareness about diseases related to bone health & osteoporosis coupled with rising disposable income levels has resulted in an increase in demand for orthobiologics over recent years at ambulatory surgical centers and clinics/hospitals across various regions including North America and Europe.


Regional Analysis:


North America dominated the global market in 2017. The presence of well-established healthcare facilities, favorable reimbursement policies, and increasing awareness levels among patients are some of the major factors responsible for this dominance. In addition, growing number of product launches is also expected to contribute towards regional growth during the forecast period.


Asia Pacific region is anticipated to witness lucrative growth over the forecast period owing to rising geriatric population and improving healthcare infrastructure along with an increase in medical tourism activities.


Growth Factors:


  • Increasing incidence of musculoskeletal disorders: The Orthobiologics market is expected to grow owing to the increasing incidence of musculoskeletal disorders such as arthritis, osteoporosis, and back pain. This is mainly because Orthobiologics products help in repairing and regenerating bone and cartilage tissues.
  • Growing geriatric population: The global geriatric population is growing at a rapid pace and this is expected to drive the demand for Orthobiologics products as these products help in restoring mobility in elderly patients suffering from joint pain or other age-related bone conditions.
  • Rising awareness about benefits of Orthobiologics: There has been a rise in the awareness about the benefits of Orthobiologics among both healthcare professionals and patients alike over the past few years. This has led to an increase in demand for these products, especially among those suffering from chronic joint pain or other orthopedic conditions.
  • Technological advancements: The orthopedic industry has witnessed significant technological advancements over the past few years, which has helped improve the efficacy of Orthobiologic treatments significantly. This is likely to boost growth prospects for this market during the forecast period . 5) Emerging markets offer untapped potential: A large number of emerging markets such as China, India, Brazil etc., offer significant growth potential for players operating inthe globalOrthobiologicssmarket due to their large population base and rising disposable incomes

Scope Of The Report

Report Attributes

Report Details

Report Title

Orthobiologics Market Research Report

By Type

Bone Growth Stimulators (BGS), Viscosupplements, Bone Graft Substitute

By Application

Hospitals, Ambulatory Surgical Centres, Orthopaedics Clinics

By Companies

Medtronic, NuVasive, Inc., Stryker Corporation, Zimmer Biomet Holdings, Orthofix International N.V., Anika Therapeutics, Inc., DePuy Synthes (Johnson & Johnson), Bioventus, Arthrex, Inc., SeaSpine Holdings Corporation, Sanofi-Aventis (Sanofi SA), Djo Global, Inc., Seikagaku Corporation, RTI Surgical, Inc., Heraeus Holding GmbH, Fidia Pharma USA Inc., TRB Chemedica International SA, Allosource, Musculoskeletal Transplant Foundation, Inc., Ito

Regions Covered

North America, Europe, APAC, Latin America, MEA

Base Year

2021

Historical Year

2019 to 2020 (Data from 2010 can be provided as per availability)

Forecast Year

2030

Number of Pages

245

Number of Tables & Figures

172

Customization Available

Yes, the report can be customized as per your need.


Global Orthobiologics Market Report Segments:

The global Orthobiologics market is segmented on the basis of:

Types

Bone Growth Stimulators (BGS), Viscosupplements, Bone Graft Substitute

The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.

Applications

Hospitals, Ambulatory Surgical Centres, Orthopaedics Clinics

The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.

Some of the companies that are profiled in this report are:

  1. Medtronic
  2. NuVasive, Inc.
  3. Stryker Corporation
  4. Zimmer Biomet Holdings
  5. Orthofix International N.V.
  6. Anika Therapeutics, Inc.
  7. DePuy Synthes (Johnson & Johnson)
  8. Bioventus
  9. Arthrex, Inc.
  10. SeaSpine Holdings Corporation
  11. Sanofi-Aventis (Sanofi SA)
  12. Djo Global, Inc.
  13. Seikagaku Corporation
  14. RTI Surgical, Inc.
  15. Heraeus Holding GmbH
  16. Fidia Pharma USA Inc.
  17. TRB Chemedica International SA
  18. Allosource
  19. Musculoskeletal Transplant Foundation, Inc.
  20. Ito

Global Orthobiologics Market Overview


Highlights of The Orthobiologics Market Report:

  1. The market structure and projections for the coming years.
  2. Drivers, restraints, opportunities, and current trends of market.
  3. Historical data and forecast.
  4. Estimations for the forecast period 2030.
  5. Developments and trends in the market.
  6. By Type:

    1. Bone Growth Stimulators (BGS)
    2. Viscosupplements
    3. Bone Graft Substitute
  1. By Application:

    1. Hospitals
    2. Ambulatory Surgical Centres
    3. Orthopaedics Clinics
  1. Market scenario by region, sub-region, and country.
  2. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
  3. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
  4. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Orthobiologics Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.

Regional Analysis

  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.

The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.

How you may use our products:

  • Correctly Positioning New Products
  • Market Entry Strategies
  • Business Expansion Strategies
  • Consumer Insights
  • Understanding Competition Scenario
  • Product & Brand Management
  • Channel & Customer Management
  • Identifying Appropriate Advertising Appeals

Global Orthobiologics Market Statistics

8 Reasons to Buy This Report

  1. Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
  2. Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
  3. Implemented Robust Methodology to Prepare the Report
  4. Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
  5. Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
  6. Provides Information About the Top-winning Strategies Implemented by Industry Players.
  7. In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
  8. Customization of the Report Available

Frequently Asked Questions?


Orthobiologics is a term used to describe the use of biologic interventions, such as medications and surgery, to treat orthopedic conditions.

Some of the key players operating in the orthobiologics market are Medtronic, NuVasive, Inc., Stryker Corporation, Zimmer Biomet Holdings, Orthofix International N.V., Anika Therapeutics, Inc., DePuy Synthes (Johnson & Johnson), Bioventus, Arthrex, Inc., SeaSpine Holdings Corporation, Sanofi-Aventis (Sanofi SA), Djo Global, Inc., Seikagaku Corporation, RTI Surgical, Inc., Heraeus Holding GmbH, Fidia Pharma USA Inc., TRB Chemedica International SA, Allosource, Musculoskeletal Transplant Foundation, Inc., Ito.

The orthobiologics market is expected to grow at a compound annual growth rate of 7.5%.

                                            
1. Executive Summary

2. Assumptions and Acronyms Used

3. Research Methodology

4. Orthobiologics Market Overview
   4.1. Introduction
      4.1.1. Market Taxonomy
      4.1.2. Market Definition
   4.2. Macro-Economic Factors
      4.2.1. Industry Outlook
   4.3. Orthobiologics Market Dynamics
      4.3.1. Market Drivers
      4.3.2. Market Restraints
      4.3.3. Opportunity
      4.3.4. Market Trends
   4.4. Orthobiologics Market - Supply Chain
   4.5. Global Orthobiologics Market Forecast
      4.5.1. Orthobiologics Market Size (US$ Mn) and Y-o-Y Growth
      4.5.2. Orthobiologics Market Size (000’ Units) and Y-o-Y Growth
      4.5.3. Orthobiologics Market Absolute $ Opportunity

5. Global Orthobiologics Market Analysis and Forecast by Type
   5.1. Market Trends
   5.2. Introduction
      5.2.1. Basis Point Share (BPS) Analysis by Type
      5.2.2. Y-o-Y Growth Projections by Type
   5.3. Orthobiologics Market Size and Volume Forecast by Type
      5.3.1. Bone Growth Stimulators (BGS)
      5.3.2. Viscosupplements
      5.3.3. Bone Graft Substitute
   5.4. Absolute $ Opportunity Assessment by Type
   5.5. Market Attractiveness/Growth Potential Analysis by Type

6. Global Orthobiologics Market Analysis and Forecast by Application
   6.1. Market Trends
   6.2. Introduction
      6.2.1. Basis Point Share (BPS) Analysis by Application
      6.2.2. Y-o-Y Growth Projections by Application
   6.3. Orthobiologics Market Size and Volume Forecast by Application
      6.3.1. Hospitals
      6.3.2. Ambulatory Surgical Centres
      6.3.3. Orthopaedics Clinics
   6.4. Absolute $ Opportunity Assessment by Application
   6.5. Market Attractiveness/Growth Potential Analysis by Application

7. Global Orthobiologics Market Analysis and Forecast by Sales Channel
   7.1. Market Trends
   7.2. Introduction
      7.2.1. Basis Point Share (BPS) Analysis by Sales Channel 
      7.2.2. Y-o-Y Growth Projections by Sales Channel
   7.3. Orthobiologics Market Size and Volume Forecast by Sales Channel 
      7.3.1. Manufacturer/Distributor/Service Provider
      7.3.2. Aftermarket
   7.4. Absolute $ Opportunity Assessment by Sales Channel
   7.5. Market Attractiveness/Growth Potential Analysis by Sales Channel

8. Global Orthobiologics Market Analysis and Forecast by Region
   8.1. Market Trends
   8.2. Introduction
      8.2.1. Basis Point Share (BPS) Analysis by Region
      8.2.2. Y-o-Y Growth Projections by Region
   8.3. Orthobiologics Market Size and Volume Forecast by Region
      8.3.1. North America
      8.3.2. Latin America
      8.3.3. Europe
      8.3.4. Asia Pacific
      8.3.5. Middle East and Africa (MEA)
   8.4. Absolute $ Opportunity Assessment by Region
   8.5. Market Attractiveness/Growth Potential Analysis by Region
   8.6. Global Orthobiologics Demand Share Forecast, 2019-2026

9. North America Orthobiologics Market Analysis and Forecast
   9.1. Introduction
      9.1.1. Basis Point Share (BPS) Analysis by Country
      9.1.2. Y-o-Y Growth Projections by Country
   9.2. North America Orthobiologics Market Size and Volume Forecast by Country
      9.2.1. U.S.
      9.2.2. Canada
   9.3. Absolute $ Opportunity Assessment by Country
   9.4. North America Orthobiologics Market Size and Volume Forecast by Application
      9.4.1. Hospitals
      9.4.2. Ambulatory Surgical Centres
      9.4.3. Orthopaedics Clinics
   9.5. Basis Point Share (BPS) Analysis by Application
   9.6. Y-o-Y Growth Projections by Application
   9.7. North America Orthobiologics Market Size and Volume Forecast by Type
      9.7.1. Bone Growth Stimulators (BGS)
      9.7.2. Viscosupplements
      9.7.3. Bone Graft Substitute
   9.8. Basis Point Share (BPS) Analysis by Type
   9.9. Y-o-Y Growth Projections by Type
   9.10. Market Attractiveness/Growth Potential Analysis
      9.10.1. By Country
      9.10.2. By Product Type
      9.10.3. By Application
      9.10.4. By Sales Channel
   9.11. North America Orthobiologics Demand Share Forecast, 2019-2026

10. Latin America Orthobiologics Market Analysis and Forecast
   10.1. Introduction
      10.1.1. Basis Point Share (BPS) Analysis by Country
      10.1.2. Y-o-Y Growth Projections by Country
      10.1.3. Latin America Average Pricing Analysis
   10.2. Latin America Orthobiologics Market Size and Volume Forecast by Country
      10.2.1. Brazil
      10.2.2. Mexico
      10.2.3. Rest of Latin America
   10.3. Absolute $ Opportunity Assessment by Country
   10.4. Latin America Orthobiologics Market Size and Volume Forecast by Application
      10.4.1. Hospitals
      10.4.2. Ambulatory Surgical Centres
      10.4.3. Orthopaedics Clinics
   10.5. Basis Point Share (BPS) Analysis by Application
   10.6. Y-o-Y Growth Projections by Application
   10.7. Latin America Orthobiologics Market Size and Volume Forecast by Type
      10.7.1. Bone Growth Stimulators (BGS)
      10.7.2. Viscosupplements
      10.7.3. Bone Graft Substitute
   10.8. Basis Point Share (BPS) Analysis by Type
   10.9. Y-o-Y Growth Projections by Type
   10.10. Market Attractiveness/Growth Potential Analysis
      10.10.1. By Country
      10.10.2. By Product Type
      10.10.3. By Application
      10.10.4. By Sales Channel
   10.11. Latin America Orthobiologics Demand Share Forecast, 2019-2026

11. Europe Orthobiologics Market Analysis and Forecast
   11.1. Introduction
      11.1.1. Basis Point Share (BPS) Analysis by Country
      11.1.2. Y-o-Y Growth Projections by Country
      11.1.3. Europe Average Pricing Analysis
   11.2. Europe Orthobiologics Market Size and Volume Forecast by Country
      11.2.1. Germany
      11.2.2. France
      11.2.3. Italy
      11.2.4. U.K.
      11.2.5. Spain
      11.2.6. Russia
      11.2.7. Rest of Europe
   11.3. Absolute $ Opportunity Assessment by Country
   11.4. Europe Orthobiologics Market Size and Volume Forecast by Application
      11.4.1. Hospitals
      11.4.2. Ambulatory Surgical Centres
      11.4.3. Orthopaedics Clinics
   11.5. Basis Point Share (BPS) Analysis by Application
   11.6. Y-o-Y Growth Projections by Application
   11.7. Europe Orthobiologics Market Size and Volume Forecast by Type
      11.7.1. Bone Growth Stimulators (BGS)
      11.7.2. Viscosupplements
      11.7.3. Bone Graft Substitute
   11.8. Basis Point Share (BPS) Analysis by Type
   11.9. Y-o-Y Growth Projections by Type
   11.10. Market Attractiveness/Growth Potential Analysis
      11.10.1. By Coutry
      11.10.2. By Product Type
      11.10.3. By Application
      11.10.4. By Sales Channel
   11.11. Europe Orthobiologics Demand Share, 2019-2026

12. Asia Pacific Orthobiologics Market Analysis and Forecast
   12.1. Introduction
      12.1.1. Basis Point Share (BPS) Analysis by Country
      12.1.2. Y-o-Y Growth Projections by Country
      12.1.3. Asia Pacific Average Pricing Analysis
   12.2. Asia Pacific Orthobiologics Market Size and Volume Forecast by Country
      12.2.1. China
      12.2.2. Japan
      12.2.3. South Korea
      12.2.4. India
      12.2.5. Australia
      12.2.6. Rest of Asia Pacific (APAC)
   12.3. Absolute $ Opportunity Assessment by Country
   12.4. Asia Pacific Orthobiologics Market Size and Volume Forecast by Application
      12.4.1. Hospitals
      12.4.2. Ambulatory Surgical Centres
      12.4.3. Orthopaedics Clinics
   12.5. Basis Point Share (BPS) Analysis by Application
   12.6. Y-o-Y Growth Projections by Application
   12.7. Asia Pacific Orthobiologics Market Size and Volume Forecast by Type
      12.7.1. Bone Growth Stimulators (BGS)
      12.7.2. Viscosupplements
      12.7.3. Bone Graft Substitute
   12.8. Basis Point Share (BPS) Analysis by Type
   12.9. Y-o-Y Growth Projections by Type
   12.10. Market Attractiveness/Growth Potential Analysis
      12.10.1. By Country
      12.10.2. By Product Type
      12.10.3. By Application
      12.10.4. By Sales Channel
   12.11. Asia Pacific Orthobiologics Demand Share, 2019-2026

13. Middle East & Africa Orthobiologics Market Analysis and Forecast
   13.1. Introduction
      13.1.1. Basis Point Share (BPS) Analysis by Country
      13.1.2. Y-o-Y Growth Projections by Country
      13.1.3. Asia Pacific Average Pricing Analysis
   13.2. Middle East & Africa Orthobiologics Market Size and Volume Forecast by Country
      13.2.1. Saudi Arabia
      13.2.2. South Africa
      13.2.3. UAE
      13.2.4. Rest of Middle East & Africa (MEA)
   13.3. Absolute $ Opportunity Assessment by Country
   13.4. Middle East & Africa Orthobiologics Market Size and Volume Forecast by Application
      13.4.1. Hospitals
      13.4.2. Ambulatory Surgical Centres
      13.4.3. Orthopaedics Clinics
   13.5. Basis Point Share (BPS) Analysis by Application
   13.6. Y-o-Y Growth Projections by Application
   13.7. Middle East & Africa Orthobiologics Market Size and Volume Forecast by Type
      13.7.1. Bone Growth Stimulators (BGS)
      13.7.2. Viscosupplements
      13.7.3. Bone Graft Substitute
   13.8. Basis Point Share (BPS) Analysis by Type
   13.9. Y-o-Y Growth Projections by Type
   13.10. Market Attractiveness/Growth Potential Analysis
      13.10.1. By Country
      13.10.2. By Product Type
      13.10.3. By Application
      13.10.4. By Sales Channel
   13.11. Middle East & Africa Orthobiologics Demand Share, 2019-2026

14. Competition Landscape
   14.1. Global Orthobiologics Market: Market Share Analysis
   14.2. Orthobiologics Distributors and Customers
   14.3. Orthobiologics Market: Competitive Dashboard
   14.4. Company Profiles (Details – Overview, Financials, Developments, Strategy) 
      14.4.1. Medtronic
         14.4.1.1. Overview
         14.4.1.2. Financials
         14.4.1.3. Developments
         14.4.1.4. Strategic Outlook
      14.4.2. NuVasive, Inc.
         14.4.2.1. Overview
         14.4.2.2. Financials
         14.4.2.3. Developments
         14.4.2.4. Strategic Outlook
      14.4.3. Stryker Corporation
         14.4.3.1. Overview
         14.4.3.2. Financials
         14.4.3.3. Developments
         14.4.3.4. Strategic Outlook
      14.4.4. Zimmer Biomet Holdings
         14.4.4.1. Overview
         14.4.4.2. Financials
         14.4.4.3. Developments
         14.4.4.4. Strategic Outlook
      14.4.5. Orthofix International N.V.
         14.4.5.1. Overview
         14.4.5.2. Financials
         14.4.5.3. Developments
         14.4.5.4. Strategic Outlook
      14.4.6. Anika Therapeutics, Inc.
         14.4.6.1. Overview
         14.4.6.2. Financials
         14.4.6.3. Developments
         14.4.6.4. Strategic Outlook
      14.4.7. DePuy Synthes (Johnson & Johnson)
         14.4.7.1. Overview
         14.4.7.2. Financials
         14.4.7.3. Developments
         14.4.7.4. Strategic Outlook
      14.4.8. Bioventus
         14.4.8.1. Overview
         14.4.8.2. Financials
         14.4.8.3. Developments
         14.4.8.4. Strategic Outlook
      14.4.9. Arthrex, Inc.
         14.4.9.1. Overview
         14.4.9.2. Financials
         14.4.9.3. Developments
         14.4.9.4. Strategic Outlook
      14.4.10. SeaSpine Holdings Corporation
         14.4.10.1. Overview
         14.4.10.2. Financials
         14.4.10.3. Developments
         14.4.10.4. Strategic Outlook
      14.4.11. Sanofi-Aventis (Sanofi SA)
         14.4.11.1. Overview
         14.4.11.2. Financials
         14.4.11.3. Developments
         14.4.11.4. Strategic Outlook
      14.4.12. Djo Global, Inc.
         14.4.12.1. Overview
         14.4.12.2. Financials
         14.4.12.3. Developments
         14.4.12.4. Strategic Outlook
      14.4.13. Seikagaku Corporation
         14.4.13.1. Overview
         14.4.13.2. Financials
         14.4.13.3. Developments
         14.4.13.4. Strategic Outlook
      14.4.14. RTI Surgical, Inc.
         14.4.14.1. Overview
         14.4.14.2. Financials
         14.4.14.3. Developments
         14.4.14.4. Strategic Outlook
      14.4.15. Heraeus Holding GmbH
         14.4.15.1. Overview
         14.4.15.2. Financials
         14.4.15.3. Developments
         14.4.15.4. Strategic Outlook
      14.4.16. Fidia Pharma USA Inc.
         14.4.16.1. Overview
         14.4.16.2. Financials
         14.4.16.3. Developments
         14.4.16.4. Strategic Outlook
      14.4.17. TRB Chemedica International SA
         14.4.17.1. Overview
         14.4.17.2. Financials
         14.4.17.3. Developments
         14.4.17.4. Strategic Outlook
      14.4.18. Allosource
         14.4.18.1. Overview
         14.4.18.2. Financials
         14.4.18.3. Developments
         14.4.18.4. Strategic Outlook
      14.4.19. Musculoskeletal Transplant Foundation, Inc.
         14.4.19.1. Overview
         14.4.19.2. Financials
         14.4.19.3. Developments
         14.4.19.4. Strategic Outlook
      14.4.20. Ito
         14.4.20.1. Overview
         14.4.20.2. Financials
         14.4.20.3. Developments
         14.4.20.4. Strategic Outlook

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