Latest Update: Impact of current COVID-19 situation has been considered in this report while making the analysis.
Global Spine Biologics Market by Type (Bone Graft, Bone Graft Substitute, Platelet Rich Plasma (PRP), BMAC (Bone Marrow Aspirate Concentrate)), By Application (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion, Other) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030-report

Global Spine Biologics Market by Type (Bone Graft, Bone Graft Substitute, Platelet Rich Plasma (PRP), BMAC (Bone Marrow Aspirate Concentrate)), By Application (Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion, Other) And By Region (North America, Latin America, Europe, Asia Pacific and Middle East & Africa), Forecast From 2022 To 2030

Report ID: 131876 3300 Medical Devices & Consumables 377 235 Pages 4.7 (44)

Market Overview:

The global spine biologics market is expected to grow at a CAGR of 7.5% from 2018 to 2030. The growth in the market can be attributed to factors such as rising incidence of spinal disorders, increasing demand for minimally invasive surgeries, and technological advancements in spine biologics products. Based on type, the global spine biologics market is segmented into bone grafts, bone graft substitutes, platelet rich plasma (PRP), and BMAC (bone marrow aspirate concentrate). Bone grafts are the most commonly used type of spine biologic and are used for fusion procedures. Platelet rich plasma is a newer product that has been gaining popularity due to its ability to promote healing and reduce inflammation. Based on application, the global spine biologics market is segmented into anterior cervical discectomy and fusion (ACDF), posterior lumbar interbody fusion (PLIF), other applications such as sacroiliac joint fusion surgery, etc., and trauma surgery. The ACDF procedure accounted for the largest share of the global spine biologics market in 2017 owing to its high prevalence rate globally.

Global Spine Biologics Industry Outlook

Product Definition:

Spine biologics are products that are used to treat spine conditions. These products can be made from natural or synthetic materials, and they can be used to replace or repair damaged tissue.

Bone Graft:

Bone graft or allograft is a procedure where bone, which is taken from a donor and implanted into the body, either in its natural position or into the spine. The process of harvesting and preparing the bone for transplantation involves several steps such as cleaning out necrotic debris from around the fracture site, debridement to clean wound bed (if any), drilling of prepared surface to accept implant and finally filling of implant with synthetic material.

Bone Graft Substitute:

Bone graft substitute is a material that can be used as a stand-in or alternative to real bone during spine surgeries. It's main function is to help surgeons while performing spinal fusion by providing structural integrity and helping the healing process of the fracture.

Application Insights:

Anterior cervical discectomy and fusion was the largest application segment in 2017. This is due to increasing number of procedures performed for the treatment of various conditions, such as herniated disc injuries or stenosis in the neck. According to a study published by NCBI, around 20 million Americans have some form of neck pain every year. In addition, another study states that around 6% to 7% of adults aged over 18 years suffer from chronic cervical pain each year in North America and Europe respectively. Therefore, growing demand for minimally invasive surgeries is expected to boost product adoption over the forecast period.

Posterior lumbar interbody fusion is anticipated register notable growth during the forecast period owing to rising incidence rate associated with low back problems among older population across developed countries including Germany, France and U.K.

Regional Analysis:

North America dominated the global market in 2017 owing to the presence of a large number of patients suffering from osteoporosis and high healthcare expenditure. According to an article published in NCBI, North America accounted for approximately 60% share of all international medical device exports in 2015. The region is expected to maintain its dominance over the forecast period due to increasing R&D investments by companies and introduction of technologically advanced products.

Asia Pacific is expected to grow at a lucrative rate during the forecast period due rising awareness about spine care, improving healthcare infrastructure, increase in patient disposable income levels coupled with government support & funding for R&D activities pertaining Spinal Biologics Market In Asia Pacific And Latin American Countries). Moreover, growing demand for minimally invasive surgeries coupled with rapidly developing economy will drive growth further. Increasing cases of spinal cord injuries are also anticipated boost regional growth over next eight years (SpineUniverse 2016).

Growth Factors:

  • Increasing incidence of spine disorders: The increasing incidence of spine disorders is one of the key growth drivers for the global spine biologics market. This is mainly due to the changing lifestyle and dietary habits, which are leading to an increase in the number of people suffering from obesity and other spine-related problems.
  • Growing demand for minimally invasive surgeries: The growing demand for minimally invasive surgeries is another major factor driving the growth of the global spine biologics market. Minimally invasive surgeries are less traumatic and result in shorter hospital stays as compared to traditional open surgery procedures. This has led to an increase in their popularity among patients worldwide.
  • Rising awareness about spinal health: There has been a rising awareness about spinal health among people around the world in recent years, which is helping to drive demand for better treatment options such as spine biologics therapies. This trend is expected to continue in future, resulting in higher growth rates for this market segment over the forecast period 2017-2025 .

Scope Of The Report

Report Attributes

Report Details

Report Title

Spine Biologics Market Research Report

By Type

Bone Graft, Bone Graft Substitute, Platelet Rich Plasma (PRP), BMAC (Bone Marrow Aspirate Concentrate)

By Application

Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion, Other

By Companies

Medtronic, Depuy Synthes, Stryker Corporation, Nuvasive, Zimmer Biomet, Orthofix International, Globus Medical, alphatec spine, K2M, Exactech, Wright Medical Technology, X-Spine, Nutech, Arthrex

Regions Covered

North America, Europe, APAC, Latin America, MEA

Base Year


Historical Year

2019 to 2020 (Data from 2010 can be provided as per availability)

Forecast Year


Number of Pages


Number of Tables & Figures


Customization Available

Yes, the report can be customized as per your need.

Global Spine Biologics Market Report Segments:

The global Spine Biologics market is segmented on the basis of:


Bone Graft, Bone Graft Substitute, Platelet Rich Plasma (PRP), BMAC (Bone Marrow Aspirate Concentrate)

The product segment provides information about the market share of each product and the respective CAGR during the forecast period. It lays out information about the product pricing parameters, trends, and profits that provides in-depth insights of the market. Furthermore, it discusses latest product developments & innovation in the market.


Anterior Cervical Discectomy and Fusion, Posterior Lumbar Interbody Fusion, Other

The application segment fragments various applications of the product and provides information on the market share and growth rate of each application segment. It discusses the potential future applications of the products and driving and restraining factors of each application segment.

Some of the companies that are profiled in this report are:

  1. Medtronic
  2. Depuy Synthes
  3. Stryker Corporation
  4. Nuvasive
  5. Zimmer Biomet
  6. Orthofix International
  7. Globus Medical
  8. alphatec spine
  9. K2M
  10. Exactech
  11. Wright Medical Technology
  12. X-Spine
  13. Nutech
  14. Arthrex

Global Spine Biologics Market Overview

Highlights of The Spine Biologics Market Report:

  1. The market structure and projections for the coming years.
  2. Drivers, restraints, opportunities, and current trends of market.
  3. Historical data and forecast.
  4. Estimations for the forecast period 2030.
  5. Developments and trends in the market.
  6. By Type:

    1. Bone Graft
    2. Bone Graft Substitute
    3. Platelet Rich Plasma (PRP)
    4. BMAC (Bone Marrow Aspirate Concentrate)
  1. By Application:

    1. Anterior Cervical Discectomy and Fusion
    2. Posterior Lumbar Interbody Fusion
    3. Other
  1. Market scenario by region, sub-region, and country.
  2. Market share of the market players, company profiles, product specifications, SWOT analysis, and competitive landscape.
  3. Analysis regarding upstream raw materials, downstream demand, and current market dynamics.
  4. Government Policies, Macro & Micro economic factors are also included in the report.

We have studied the Spine Biologics Market in 360 degrees via. both primary & secondary research methodologies. This helped us in building an understanding of the current market dynamics, supply-demand gap, pricing trends, product preferences, consumer patterns & so on. The findings were further validated through primary research with industry experts & opinion leaders across countries. The data is further compiled & validated through various market estimation & data validation methodologies. Further, we also have our in-house data forecasting model to predict market growth up to 2030.

Regional Analysis

  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

Note: A country of choice can be added in the report at no extra cost. If more than one country needs to be added, the research quote will vary accordingly.

The geographical analysis part of the report provides information about the product sales in terms of volume and revenue in regions. It lays out potential opportunities for the new entrants, emerging players, and major players in the region. The regional analysis is done after considering the socio-economic factors and government regulations of the countries in the regions.

How you may use our products:

  • Correctly Positioning New Products
  • Market Entry Strategies
  • Business Expansion Strategies
  • Consumer Insights
  • Understanding Competition Scenario
  • Product & Brand Management
  • Channel & Customer Management
  • Identifying Appropriate Advertising Appeals

Global Spine Biologics Market Statistics

8 Reasons to Buy This Report

  1. Includes a Chapter on the Impact of COVID-19 Pandemic On the Market
  2. Report Prepared After Conducting Interviews with Industry Experts & Top Designates of the Companies in the Market
  3. Implemented Robust Methodology to Prepare the Report
  4. Includes Graphs, Statistics, Flowcharts, and Infographics to Save Time
  5. Industry Growth Insights Provides 24/5 Assistance Regarding the Doubts in the Report
  6. Provides Information About the Top-winning Strategies Implemented by Industry Players.
  7. In-depth Insights On the Market Drivers, Restraints, Opportunities, and Threats
  8. Customization of the Report Available
1. Executive Summary

2. Assumptions and Acronyms Used

3. Research Methodology

4. Spine Biologics Market Overview
   4.1. Introduction
      4.1.1. Market Taxonomy
      4.1.2. Market Definition
   4.2. Macro-Economic Factors
      4.2.1. Industry Outlook
   4.3. Spine Biologics Market Dynamics
      4.3.1. Market Drivers
      4.3.2. Market Restraints
      4.3.3. Opportunity
      4.3.4. Market Trends
   4.4. Spine Biologics Market - Supply Chain
   4.5. Global Spine Biologics Market Forecast
      4.5.1. Spine Biologics Market Size (US$ Mn) and Y-o-Y Growth
      4.5.2. Spine Biologics Market Size (000’ Units) and Y-o-Y Growth
      4.5.3. Spine Biologics Market Absolute $ Opportunity

5. Global Spine Biologics Market Analysis and Forecast by Type
   5.1. Market Trends
   5.2. Introduction
      5.2.1. Basis Point Share (BPS) Analysis by Type
      5.2.2. Y-o-Y Growth Projections by Type
   5.3. Spine Biologics Market Size and Volume Forecast by Type
      5.3.1. Bone Graft
      5.3.2. Bone Graft Substitute
      5.3.3. Platelet Rich Plasma (PRP)
      5.3.4. BMAC (Bone Marrow Aspirate Concentrate)
   5.4. Absolute $ Opportunity Assessment by Type
   5.5. Market Attractiveness/Growth Potential Analysis by Type

6. Global Spine Biologics Market Analysis and Forecast by Application
   6.1. Market Trends
   6.2. Introduction
      6.2.1. Basis Point Share (BPS) Analysis by Application
      6.2.2. Y-o-Y Growth Projections by Application
   6.3. Spine Biologics Market Size and Volume Forecast by Application
      6.3.1. Anterior Cervical Discectomy and Fusion
      6.3.2. Posterior Lumbar Interbody Fusion
      6.3.3. Other
   6.4. Absolute $ Opportunity Assessment by Application
   6.5. Market Attractiveness/Growth Potential Analysis by Application

7. Global Spine Biologics Market Analysis and Forecast by Sales Channel
   7.1. Market Trends
   7.2. Introduction
      7.2.1. Basis Point Share (BPS) Analysis by Sales Channel 
      7.2.2. Y-o-Y Growth Projections by Sales Channel
   7.3. Spine Biologics Market Size and Volume Forecast by Sales Channel 
      7.3.1. Manufacturer/Distributor/Service Provider
      7.3.2. Aftermarket
   7.4. Absolute $ Opportunity Assessment by Sales Channel
   7.5. Market Attractiveness/Growth Potential Analysis by Sales Channel

8. Global Spine Biologics Market Analysis and Forecast by Region
   8.1. Market Trends
   8.2. Introduction
      8.2.1. Basis Point Share (BPS) Analysis by Region
      8.2.2. Y-o-Y Growth Projections by Region
   8.3. Spine Biologics Market Size and Volume Forecast by Region
      8.3.1. North America
      8.3.2. Latin America
      8.3.3. Europe
      8.3.4. Asia Pacific
      8.3.5. Middle East and Africa (MEA)
   8.4. Absolute $ Opportunity Assessment by Region
   8.5. Market Attractiveness/Growth Potential Analysis by Region
   8.6. Global Spine Biologics Demand Share Forecast, 2019-2029

9. North America Spine Biologics Market Analysis and Forecast
   9.1. Introduction
      9.1.1. Basis Point Share (BPS) Analysis by Country
      9.1.2. Y-o-Y Growth Projections by Country
   9.2. North America Spine Biologics Market Size and Volume Forecast by Country
      9.2.1. U.S.
      9.2.2. Canada
   9.3. Absolute $ Opportunity Assessment by Country
   9.4. North America Spine Biologics Market Size and Volume Forecast by Application
      9.4.1. Anterior Cervical Discectomy and Fusion
      9.4.2. Posterior Lumbar Interbody Fusion
      9.4.3. Other
   9.5. Basis Point Share (BPS) Analysis by Application
   9.6. Y-o-Y Growth Projections by Application
   9.7. North America Spine Biologics Market Size and Volume Forecast by Type
      9.7.1. Bone Graft
      9.7.2. Bone Graft Substitute
      9.7.3. Platelet Rich Plasma (PRP)
      9.7.4. BMAC (Bone Marrow Aspirate Concentrate)
   9.8. Basis Point Share (BPS) Analysis by Type
   9.9. Y-o-Y Growth Projections by Type
   9.10. Market Attractiveness/Growth Potential Analysis
      9.10.1. By Country
      9.10.2. By Product Type
      9.10.3. By Application
      9.10.4. By Sales Channel
   9.11. North America Spine Biologics Demand Share Forecast, 2019-2029

10. Latin America Spine Biologics Market Analysis and Forecast
   10.1. Introduction
      10.1.1. Basis Point Share (BPS) Analysis by Country
      10.1.2. Y-o-Y Growth Projections by Country
      10.1.3. Latin America Average Pricing Analysis
   10.2. Latin America Spine Biologics Market Size and Volume Forecast by Country
      10.2.1. Brazil
      10.2.2. Mexico
      10.2.3. Rest of Latin America
   10.3. Absolute $ Opportunity Assessment by Country
   10.4. Latin America Spine Biologics Market Size and Volume Forecast by Application
      10.4.1. Anterior Cervical Discectomy and Fusion
      10.4.2. Posterior Lumbar Interbody Fusion
      10.4.3. Other
   10.5. Basis Point Share (BPS) Analysis by Application
   10.6. Y-o-Y Growth Projections by Application
   10.7. Latin America Spine Biologics Market Size and Volume Forecast by Type
      10.7.1. Bone Graft
      10.7.2. Bone Graft Substitute
      10.7.3. Platelet Rich Plasma (PRP)
      10.7.4. BMAC (Bone Marrow Aspirate Concentrate)
   10.8. Basis Point Share (BPS) Analysis by Type
   10.9. Y-o-Y Growth Projections by Type
   10.10. Market Attractiveness/Growth Potential Analysis
      10.10.1. By Country
      10.10.2. By Product Type
      10.10.3. By Application
      10.10.4. By Sales Channel
   10.11. Latin America Spine Biologics Demand Share Forecast, 2019-2029

11. Europe Spine Biologics Market Analysis and Forecast
   11.1. Introduction
      11.1.1. Basis Point Share (BPS) Analysis by Country
      11.1.2. Y-o-Y Growth Projections by Country
      11.1.3. Europe Average Pricing Analysis
   11.2. Europe Spine Biologics Market Size and Volume Forecast by Country
      11.2.1. Germany
      11.2.2. France
      11.2.3. Italy
      11.2.4. U.K.
      11.2.5. Spain
      11.2.6. Russia
      11.2.7. Rest of Europe
   11.3. Absolute $ Opportunity Assessment by Country
   11.4. Europe Spine Biologics Market Size and Volume Forecast by Application
      11.4.1. Anterior Cervical Discectomy and Fusion
      11.4.2. Posterior Lumbar Interbody Fusion
      11.4.3. Other
   11.5. Basis Point Share (BPS) Analysis by Application
   11.6. Y-o-Y Growth Projections by Application
   11.7. Europe Spine Biologics Market Size and Volume Forecast by Type
      11.7.1. Bone Graft
      11.7.2. Bone Graft Substitute
      11.7.3. Platelet Rich Plasma (PRP)
      11.7.4. BMAC (Bone Marrow Aspirate Concentrate)
   11.8. Basis Point Share (BPS) Analysis by Type
   11.9. Y-o-Y Growth Projections by Type
   11.10. Market Attractiveness/Growth Potential Analysis
      11.10.1. By Country
      11.10.2. By Product Type
      11.10.3. By Application
      11.10.4. By Sales Channel
   11.11. Europe Spine Biologics Demand Share, 2019-2029

12. Asia Pacific Spine Biologics Market Analysis and Forecast
   12.1. Introduction
      12.1.1. Basis Point Share (BPS) Analysis by Country
      12.1.2. Y-o-Y Growth Projections by Country
      12.1.3. Asia Pacific Average Pricing Analysis
   12.2. Asia Pacific Spine Biologics Market Size and Volume Forecast by Country
      12.2.1. China
      12.2.2. Japan
      12.2.3. South Korea
      12.2.4. India
      12.2.5. Australia
      12.2.6. Rest of Asia Pacific (APAC)
   12.3. Absolute $ Opportunity Assessment by Country
   12.4. Asia Pacific Spine Biologics Market Size and Volume Forecast by Application
      12.4.1. Anterior Cervical Discectomy and Fusion
      12.4.2. Posterior Lumbar Interbody Fusion
      12.4.3. Other
   12.5. Basis Point Share (BPS) Analysis by Application
   12.6. Y-o-Y Growth Projections by Application
   12.7. Asia Pacific Spine Biologics Market Size and Volume Forecast by Type
      12.7.1. Bone Graft
      12.7.2. Bone Graft Substitute
      12.7.3. Platelet Rich Plasma (PRP)
      12.7.4. BMAC (Bone Marrow Aspirate Concentrate)
   12.8. Basis Point Share (BPS) Analysis by Type
   12.9. Y-o-Y Growth Projections by Type
   12.10. Market Attractiveness/Growth Potential Analysis
      12.10.1. By Country
      12.10.2. By Product Type
      12.10.3. By Application
      12.10.4. By Sales Channel
   12.11. Asia Pacific Spine Biologics Demand Share, 2019-2029

13. Middle East & Africa Spine Biologics Market Analysis and Forecast
   13.1. Introduction
      13.1.1. Basis Point Share (BPS) Analysis by Country
      13.1.2. Y-o-Y Growth Projections by Country
      13.1.3. Asia Pacific Average Pricing Analysis
   13.2. Middle East & Africa Spine Biologics Market Size and Volume Forecast by Country
      13.2.1. Saudi Arabia
      13.2.2. South Africa
      13.2.3. UAE
      13.2.4. Rest of Middle East & Africa (MEA)
   13.3. Absolute $ Opportunity Assessment by Country
   13.4. Middle East & Africa Spine Biologics Market Size and Volume Forecast by Application
      13.4.1. Anterior Cervical Discectomy and Fusion
      13.4.2. Posterior Lumbar Interbody Fusion
      13.4.3. Other
   13.5. Basis Point Share (BPS) Analysis by Application
   13.6. Y-o-Y Growth Projections by Application
   13.7. Middle East & Africa Spine Biologics Market Size and Volume Forecast by Type
      13.7.1. Bone Graft
      13.7.2. Bone Graft Substitute
      13.7.3. Platelet Rich Plasma (PRP)
      13.7.4. BMAC (Bone Marrow Aspirate Concentrate)
   13.8. Basis Point Share (BPS) Analysis by Type
   13.9. Y-o-Y Growth Projections by Type
   13.10. Market Attractiveness/Growth Potential Analysis
      13.10.1. By Country
      13.10.2. By Product Type
      13.10.3. By Application
      13.10.4. By Sales Channel
   13.11. Middle East & Africa Spine Biologics Demand Share, 2019-2029

14. Competition Landscape
   14.1. Global Spine Biologics Market: Market Share Analysis
   14.2. Spine Biologics Distributors and Customers
   14.3. Spine Biologics Market: Competitive Dashboard
   14.4. Company Profiles (Details – Overview, Financials, Developments, Strategy) 
      14.4.1. Medtronic Overview Financials Developments Strategic Outlook
      14.4.2. Depuy Synthes Overview Financials Developments Strategic Outlook
      14.4.3. Stryker Corporation Overview Financials Developments Strategic Outlook
      14.4.4. Nuvasive Overview Financials Developments Strategic Outlook
      14.4.5. Zimmer Biomet Overview Financials Developments Strategic Outlook
      14.4.6. Orthofix International Overview Financials Developments Strategic Outlook
      14.4.7. Globus Medical Overview Financials Developments Strategic Outlook
      14.4.8. alphatec spine Overview Financials Developments Strategic Outlook
      14.4.9. K2M Overview Financials Developments Strategic Outlook
      14.4.10. Exactech Overview Financials Developments Strategic Outlook
      14.4.11. Wright Medical Technology Overview Financials Developments Strategic Outlook
      14.4.12. X-Spine Overview Financials Developments Strategic Outlook
      14.4.13. Nutech Overview Financials Developments Strategic Outlook
      14.4.14. Arthrex Overview Financials Developments Strategic Outlook
      14.4.15. COMPANY 15 Overview Financials Developments Strategic Outlook
      14.4.16. COMPANY 16 Overview Financials Developments Strategic Outlook
      14.4.17. COMPANY 17 Overview Financials Developments Strategic Outlook
      14.4.18. COMPANY 18 Overview Financials Developments Strategic Outlook
      14.4.19. COMPANY 19 Overview Financials Developments Strategic Outlook
      14.4.20. COMPANY 20 Overview Financials Developments Strategic Outlook

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